Literature DB >> 6312905

Comparative studies on the amoebicidal activity of known 5-nitroimidazole derivatives and CG 10213-Go in golden hamsters, Mesocricetus auratus, infected in the liver or caecum or both with trophozoites of Entamoeba histolytica.

D K Ray, V B Shrivastava, J S Tendulkar, A K Dutta, K K Bhopale, D K Chatterjee, K Nagarajan.   

Abstract

CG 10213-Go, a 5-nitroimidazole derivative synthesized at the CIBA-Geigy Research Centre, Bombay, proved superior to such currently used 5-nitroimidazole derivatives as metronidazole, ornidazole, secnidazole, tinidazole and nimorazole, against experimental amoebic infections of the liver and caecum in a golden hamster model. CG 10213-Go is now undergoing clinical trials.

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Year:  1983        PMID： 6312905     DOI： 10.1080/00034983.1983.11811709

Source DB:  PubMed          Journal:  Ann Trop Med Parasitol        ISSN： 0003-4983


  2 in total

1.  Randomized, single-blind, placebo-controlled multicenter trial to compare the efficacy and safety of metronidazole and satranidazole in patients with amebic liver abscess.

Authors:  Jameel Muzaffar; Kaushal Madan; M P Sharma; Premashish Kar
Journal:  Dig Dis Sci       Date:  2006-11-11       Impact factor: 3.487

2.  Clinical and microbiological efficacy of 3% satranidazole gel as a local drug delivery system in the treatment of chronic periodontitis: A randomized, controlled clinical trial.

Authors:  N Priyanka; Nitish Kalra; Shahab Saquib; Nitin Kudyar; Nikhil Malgaonkar; Hunny Jain; A R Pradeep
Journal:  Contemp Clin Dent       Date:  2015 Jul-Sep
  2 in total

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