Literature DB >> 631278

Effect of dimethyl sulfate on the secondary structure of DNA.

A A Wani, S M Hadi, N S Ahmad.   

Abstract

Hydroxyapatite chromatography has been used to demonstrate that alkylation of DNA at neutral pH may lead to denaturation under conditions where no significant depurination occurs. Presence of salt has a preventive effect on such denaturation.

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Year:  1978        PMID： 631278     DOI： 10.1007/bf01923056

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  8 in total

1.  Effects of alkylation by dimethyl sulfate, nitrogen mustard, and mitomycin C on DNA structure as studied by the ethidium binding assay.

Authors:  H Hsiung; J W Lown
Journal:  Can J Biochem       Date:  1976-12

2.  FURTHER STUDIES ON THE ALKYLATION OF NUCLEIC ACIDS AND THEIR CONSTITUENT NUCLEOTIDES.

Authors:  P D LAWLEY; P BROOKES
Journal:  Biochem J       Date:  1963-10       Impact factor: 3.857

3.  Distribution density of nucleotides within a desoxyribonucleic acid chain.

Authors:  C TAMM; H S SHAPIRO; R LIPSHITZ; E CHARGAFF
Journal:  J Biol Chem       Date:  1953-08       Impact factor: 5.157

4.  Physicochemical changes produced in DNA after alkylation.

Authors:  J T LETT; G M PARKINS; P ALEXANDER
Journal:  Arch Biochem Biophys       Date:  1962-04       Impact factor: 4.013

5.  Nuclease for DNA apurinic sites may be involved in the maintenance of DNA in normal cells.

Authors:  W G Verly; Y Paquette; L Thibodeau
Journal:  Nat New Biol       Date:  1973-07-18

6.  Nuclease for DNA apurinic sites in chicken liver.

Authors:  R Y Rizvi; S M Hadi
Journal:  Experientia       Date:  1977-04-15

7.  Alkylation of phosphates and stability of phosphate triesters in DNA.

Authors:  P Bannon; W Verly
Journal:  Eur J Biochem       Date:  1972-11-21

8.  Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N'-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation.

Authors:  P D Lawley; C J Thatcher
Journal:  Biochem J       Date:  1970-02       Impact factor: 3.857
  8 in total

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