Literature DB >> 631257

Mutagenicity testing of 3 hallucinogens: LSD, psilocybin and delta 9-THC, using the micronucleus test.

G F Van Went.   

Abstract

Using the micronucleus test as a screening method for mutagenic activity, no significant increase in the number of micronuclei was found when LSD, psilocybin or delta 9-THC were administered in 3 logarithmically increasing doses to mice, Azathioiprine (Imuran), given as a positive control, caused a statistically significantt increase in the micronucleated cells.

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Year:  1978        PMID： 631257     DOI： 10.1007/bf01923013

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  14 in total

1.  Chromosome examinations after medically administered lysergic acid diethylamide and dextroamphetamine.

Authors:  L F Jarvik; F S Yen; C C Dahlberg; J L Fleiss; J Jaffe; T Kato; E Moralishvili
Journal:  Dis Nerv Syst       Date:  1974-09

2.  Marihuana: the grass may no longer be greener.

Authors:  T H Maugh
Journal:  Science       Date:  1974-08-23       Impact factor: 47.728

3.  The mutagenic effect of lysergic acid diethylamide. II. Dominant lethal test in mice.

Authors:  R J Srám; Z Zudová; P Goetz
Journal:  Mutat Res       Date:  1974-12       Impact factor: 2.433

4.  The mutagenic effect of lysergic acid diethylamide. I. Cytogenetic analysis.

Authors:  P Goetz; R J Srám; Z Zudová
Journal:  Mutat Res       Date:  1974-12       Impact factor: 2.433

5.  Cytogenetic studies on human subjects receiving marihuana and delta 9-tetrahydrocannabinol.

Authors:  W W Nichols; R C Miller; W Heneen; C Bradt; L Hollister; S Kanter
Journal:  Mutat Res       Date:  1974-10       Impact factor: 2.433

6.  Chromosome breakage in users of marihuana.

Authors:  M A Stenchever; T J Kunysz; M A Allen
Journal:  Am J Obstet Gynecol       Date:  1974-01-01       Impact factor: 8.661

7.  Effects of marihuana and lysergic acid diethylamide on leukocyte chromosomes of the golden hamster.

Authors:  M T Nicholson; H B Pace; W M Davis
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1973-09

8.  LSD--an in vivo retrospective chromosome study.

Authors:  J Fernandez; I W Browne; J Cullen; T Brennan; H Matheu; I Fischer; J Masterson; E Law
Journal:  Ann Hum Genet       Date:  1973-07       Impact factor: 1.670

9.  [Chemical mutagenesis in mammals. The Chinese hamster bone marrow as an in vivo test system. Hematological findings after treatment with trenimon].

Authors:  K Boller; W Schmid
Journal:  Humangenetik       Date:  1970

10.  Marijuana exposure in vivo and human lymphocyte chromosomes.

Authors:  S S Matsuyama; F S Yen; L F Jarvik; R S Sparkes; T K Fu; H Fisher; N Reccius; I M Frank
Journal:  Mutat Res       Date:  1977-04       Impact factor: 2.433
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  7 in total

Review 1.  The abuse potential of medical psilocybin according to the 8 factors of the Controlled Substances Act.

Authors:  Matthew W Johnson; Roland R Griffiths; Peter S Hendricks; Jack E Henningfield
Journal:  Neuropharmacology       Date:  2018-06-05       Impact factor: 5.250

Review 2.  The analgesic potential of cannabinoids.

Authors:  Jaseena Elikkottil; Jaseena Elikottil; Pankaj Gupta; Kalpna Gupta
Journal:  J Opioid Manag       Date:  2009 Nov-Dec

Review 3.  Impacts of cannabinoid epigenetics on human development: reflections on Murphy et. al. 'cannabinoid exposure and altered DNA methylation in rat and human sperm' epigenetics 2018; 13: 1208-1221.

Authors:  Albert Stuart Reece; Gary Kenneth Hulse
Journal:  Epigenetics       Date:  2019-07-11       Impact factor: 4.528

4.  Cannabis Consumption Patterns Explain the East-West Gradient in Canadian Neural Tube Defect Incidence: An Ecological Study.

Authors:  Albert Stuart Reece; Gary Kenneth Hulse
Journal:  Glob Pediatr Health       Date:  2019-12-11

5.  Genotoxicity of Marijuana in Mono-Users.

Authors:  Eunice Fabian-Morales; Carmen Fernández-Cáceres; Adriana Gudiño; Marco A Andonegui Elguera; Karla Torres-Arciga; Marco Armando Escobar Arrazola; Laura Tolentino García; Yair E Alfaro Mora; Diego A Oliva-Rico; Rodrigo E Cáceres Gutiérrez; Julieta Domínguez Ortíz; Clementina Castro Hernández; Luis A Herrera Montalvo; David Bruno Díaz-Negrete; Nancy Reynoso-Noverón
Journal:  Front Psychiatry       Date:  2021-12-06       Impact factor: 4.157

Review 6.  Psilocybin for Treating Psychiatric Disorders: A Psychonaut Legend or a Promising Therapeutic Perspective?

Authors:  Maurizio Coppola; Francesco Bevione; Raffaella Mondola
Journal:  J Xenobiot       Date:  2022-02-07

7.  Canadian Cannabis Consumption and Patterns of Congenital Anomalies: An Ecological Geospatial Analysis.

Authors:  Albert Stuart Reece; Gary Kenneth Hulse
Journal:  J Addict Med       Date:  2020 Sep/Oct       Impact factor: 4.647
  7 in total

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