Literature DB >> 6312326

Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor.

K C Robbins, H N Antoniades, S G Devare, M W Hunkapiller, S A Aaronson.   

Abstract

The predicted amino acid sequence of the simian sarcoma virus (SSV) transforming gene product, p28sis, closely corresponds to that of human platelet-derived growth factor (PDGF). We demonstrate that p28sis rapidly undergoes a series of discrete processing steps including dimer formation and proteolytic digestion to yield molecules structurally and immunologically resembling biologically active PDGF.

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Year:  1983        PMID： 6312326     DOI： 10.1038/305605a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  84 in total

1.  The 56 kd platelet-derived growth factor (PDGF)-related protein is phosphorylated and the most stable form in human glioma cells.

Authors:  T Nakamura; I Takeshita; T Inamura; M Fukui
Journal:  J Neurooncol       Date:  1992-06       Impact factor: 4.130

Review 2.  Molecular mimicry as a mechanism for virus-induced autoimmunity.

Authors:  R S Fujinami; M B Oldstone
Journal:  Immunol Res       Date:  1989       Impact factor: 2.829

3.  Members of the src and ras oncogene families supplant the epidermal growth factor requirement of BALB/MK-2 keratinocytes and induce distinct alterations in their terminal differentiation program.

Authors:  B Weissman; S A Aaronson
Journal:  Mol Cell Biol       Date:  1985-12       Impact factor: 4.272

4.  Expression and purification of biologically active v-sis/platelet-derived growth factor B protein by using a baculovirus vector system.

Authors:  N Giese; M May-Siroff; W J LaRochelle; K van Wyke Coelingh; S A Aaronson
Journal:  J Virol       Date:  1989-07       Impact factor: 5.103

5.  Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways.

Authors:  T Matsui; J H Pierce; T P Fleming; J S Greenberger; W J LaRochelle; M Ruggiero; S A Aaronson
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

6.  Translocation of c-abl oncogene and PDGFB (c-sis) gene in a case of CML with 46,XY, t(22;22).

Authors:  G Gradl; H Tesch; G Schwieder; T Wagner; C Fonatsch
Journal:  Blut       Date:  1989-06

7.  Deletions in the C-terminal coding region of the v-sis gene: dimerization is required for transformation.

Authors:  M Hannink; M K Sauer; D J Donoghue
Journal:  Mol Cell Biol       Date:  1986-04       Impact factor: 4.272

8.  Identification of a cell retention signal in the B-chain of platelet-derived growth factor and in the long splice version of the A-chain.

Authors:  A Ostman; M Andersson; C Betsholtz; B Westermark; C H Heldin
Journal:  Cell Regul       Date:  1991-07

9.  Induction of c-sis gene expression and synthesis of platelet-derived growth factor in human myeloid leukemia cells during monocytic differentiation.

Authors:  P Pantazis; E Sariban; D Kufe; H N Antoniades
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

10.  Human leukemia cells synthesize and secrete proteins related to platelet-derived growth factor.

Authors:  P Pantazis; L Lanfrancone; P G Pelicci; R Dalla-Favera; H N Antoniades
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205
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