| Literature DB >> 6311784 |
F Soriano, C Ponte, M Santamaría.
Abstract
The activity of cefotaxime and metronidazole against one strain of Escherichia coli and three of Bacteroides has been studied. A fixed cefotaxime concentration (8 mg/l) did not kill E. coli in presence of Bacteroides due to degradation of the drug by the anaerobe. However, the presence of metronidazole in the same system killed Bacteroides strains very effectively and prevented the degradation of cefotaxime which killed E. coli.Entities:
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Year: 1983 PMID： 6311784 DOI： 10.1093/jac/12.1.89
Source DB: PubMed Journal: J Antimicrob Chemother ISSN： 0305-7453 Impact factor: 5.790