| Literature DB >> 6311595 |
D Ghose, E Weiss, J C Homo, M H Van Regenmortel, P Oudet.
Abstract
The unique capabilities of the scanning transmission electron microscope (STEM) have been used for a high resolution study of antibody binding to individual SV40 minichromosomes. A method of sample preparation has been developed which allows direct visualization of the antibody molecules in a clearly recognizable form. Using this technique, we have studied the binding of anti-H2B and anti-H3 immunoglobulins to SV40 minichromosomes. The results indicate that histones H2B and H3 are located only in the nucleosomes and are absent in the linker regions.Entities:
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Year: 1983 PMID： 6311595 DOI： 10.1016/0014-4827(83)90278-1
Source DB: PubMed Journal: Exp Cell Res ISSN： 0014-4827 Impact factor: 3.905