Literature DB >> 6311330

Does low pH stimulate central chemoreceptors located near the ventral medullary surface?

R Miles.   

Abstract

An in vitro preparation of the medulla oblongata of the rat was used to examine the responses to reducing pH, at constant CO2, of neurons in several identified nuclei. Neurons in an area close to the ventral surface, which is thought to be the location of pH-sensitive central respiratory chemoreceptors, did not respond differently from neurons in other medullary nuclei.

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Year:  1983        PMID: 6311330     DOI: 10.1016/0006-8993(83)90300-1

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  11 in total

1.  Characterization of the chemosensitive response of individual solitary complex neurons from adult rats.

Authors:  Nicole L Nichols; Daniel K Mulkey; Katherine A Wilkinson; Frank L Powell; Jay B Dean; Robert W Putnam
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2009-01-14       Impact factor: 3.619

2.  Effect of sinus denervation and vagotomy on c-fos expression in the nucleus tractus solitarius after exposure to CO2.

Authors:  A H Jansen; P Liu; H Weisman; V Chernick; D M Nance
Journal:  Pflugers Arch       Date:  1996-04       Impact factor: 3.657

3.  Quantification of the response of rat medullary raphe neurones to independent changes in pH(o) and P(CO2).

Authors:  Wengang Wang; Stefania Risso Bradley; George B Richerson
Journal:  J Physiol       Date:  2002-05-01       Impact factor: 5.182

4.  CO2 decreases membrane conductance and depolarizes neurons in the nucleus tractus solitarii.

Authors:  J B Dean; W L Lawing; D E Millhorn
Journal:  Exp Brain Res       Date:  1989       Impact factor: 1.972

5.  Neurons sensitive to pH in slices of the rat ventral medulla oblongata.

Authors:  W Jarolimek; U Misgeld; H D Lux
Journal:  Pflugers Arch       Date:  1990-05       Impact factor: 3.657

6.  Central CO2 chemoreception in cardiorespiratory control.

Authors:  Jay B Dean; Eugene E Nattie
Journal:  J Appl Physiol (1985)       Date:  2010-02-11

7.  Modulation of the centrally-evoked visceral alerting/defence response by changes in CSF pH at the ventral surface of the medulla oblongata and by systemic hypercapnia.

Authors:  J M Marshall
Journal:  Pflugers Arch       Date:  1986-07       Impact factor: 3.657

8.  GFP-expressing locus ceruleus neurons from Prp57 transgenic mice exhibit CO2/H+ responses in primary cell culture.

Authors:  Shereé M Johnson; Musa A Haxhiu; George B Richerson
Journal:  J Appl Physiol (1985)       Date:  2008-07-17

Review 9.  Role of chemoreceptors in mediating dyspnea.

Authors:  Gordon F Buchanan; George B Richerson
Journal:  Respir Physiol Neurobiol       Date:  2008-12-11       Impact factor: 1.931

10.  Chemosensory responses to CO2 in multiple brain stem nuclei determined using a voltage-sensitive dye in brain slices from rats.

Authors:  Joseph S Erlichman; Andrew C Boyer; Patrick Reagan; Robert W Putnam; Nick A Ritucci; J C Leiter
Journal:  J Neurophysiol       Date:  2009-06-24       Impact factor: 2.714

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