| Literature DB >> 6311188 |
O M Conneely, J M Greene, D R Headon, J Hsiao, F Ungar.
Abstract
Membrane cholesterol in adrenal cortical cells is enriched in the plasma membrane. Stimulation of isolated adrenal cortical cells with corticotropin leads to the production of corticosterone. At high levels of corticotropin, cholesterol for corticosterone synthesis arises by hydrolysis of cellular cholesteryl ester, whereas at lower levels of corticotropin cholesteryl ester levels are unchanged from control values and there is a decrease in plasma-membrane cholesterol levels.Entities:
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Year: 1983 PMID： 6311188 PMCID： PMC1152281 DOI： 10.1042/bj2140561
Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857