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Literature DB >> 6311092

Cefmenoxime penetration into gallbladder bile and tissue.

Abstract

Cefmenoxime concentrations in gallbladder bile and tissue were assessed in patients undergoing cholecystectomy. A 0.5-g intravenous dose produced mean concentrations in bile of 54.1 micrograms/ml at 62.9 min and 56.3 micrograms/ml at 194 min after the dose was given. A 1.0-g intravenous dose produced concentrations in bile of 117.9 micrograms/ml at 53 min and 169.7 micrograms/ml of 194 min after the dose was given. Mean concentrations in tissue ranged from 6.1 to 17.9 micrograms/g. Biliary tree penetration was dose and time dependent. Therapeutic concentrations were achieved.

Entities: Chemical Species

Mesh：

Substances：
Cefmenoxime
Cefotaxime

Year: 1983 PMID： 6311092 PMCID： PMC185014 DOI： 10.1128/AAC.23.6.941

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

1. Antibiotic treatment of biliary sepsis.

Authors: M R Keighley; R B Drysdale; A H Quoraishi; D W Burdon; J Alexander-Williams
Journal: Surg Clin North Am Date: 1975-12 Impact factor: 2.741

2. The bacteriology of the obstructed biliary tree.

Authors: A C Maddocks; G R Hilson; R Taylor
Journal: Ann R Coll Surg Engl Date: 1973-05 Impact factor: 1.891

3. Bacteria and biliary tract disease.

Authors: J T Goswitz
Journal: Am J Surg Date: 1974-11 Impact factor: 2.565

4. Gallbladder bacteriology, histology, and gallstones. Study of unselected cholecystectomy specimens in Honolulu.

Authors: F H Fukunaga
Journal: Arch Surg Date: 1973-02

5. Bacteriology of calculous cholecystitis.

Authors: H Chaitin
Journal: Int Surg Date: 1973-03

6. Bacteriology and antibiotic selection in biliary tract surgery.

Authors: G R Mason
Journal: Arch Surg Date: 1968-10

7. Biliary bacteremia.

Authors: S H Chetlin; D W Elliott
Journal: Arch Surg Date: 1971-04

8. Cefmenoxime (SCE-1365), a new cephalosporin: in vitro activity, comparison with other antimicrobial agents, beta-lactamase stability, and disk diffusion testing with tentative interpretive criteria.

Authors: P C Fuchs; R N Jones; C Thornsberry; A L Barry; E H Gerlach; H M Sommers
Journal: Antimicrob Agents Chemother Date: 1981-12 Impact factor: 5.191

Cefmenoxime penetration into gallbladder bile and tissue.

1. Antibiotic treatment of biliary sepsis.

2. The bacteriology of the obstructed biliary tree.

3. Bacteria and biliary tract disease.

4. Gallbladder bacteriology, histology, and gallstones. Study of unselected cholecystectomy specimens in Honolulu.

5. Bacteriology of calculous cholecystitis.

6. Bacteriology and antibiotic selection in biliary tract surgery.

7. Biliary bacteremia.

8. Cefmenoxime (SCE-1365), a new cephalosporin: in vitro activity, comparison with other antimicrobial agents, beta-lactamase stability, and disk diffusion testing with tentative interpretive criteria.

9. In vitro activity and beta-lactamase stability of cefmenoxime.

10. Antimicrobial activity of cefmenoxime (SCE-1365).

Review 1. Cefmenoxime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

2. Cefmenoxime pharmacokinetics in patients with renal insufficiency.

3. Antimicrobial activities of BMY-28142, cefbuperazone, and cefpiramide compared with those of other cephalosporins.