Literature DB >> 6310688

Blood platelets in psychopharmacological research.

A Rotman.   

Abstract

Blood platelets are a very good model for nerve endings, for study of serotonin uptake and imipramine binding. The efficiency of various drugs, mainly antidepressants, can be evaluated using blood platelets instead of synaptosomes. A few neuronal active compounds are effective in inducing platelet secretion and shape change reaction. Platelet MAO and c-AMP levels are not yet established as useful in psychopharmacological studies.

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Year:  1983        PMID： 6310688     DOI： 10.1016/0278-5846(83)90101-x

Source DB:  PubMed          Journal:  Prog Neuropsychopharmacol Biol Psychiatry        ISSN： 0278-5846            Impact factor:   5.067


  3 in total

1.  Effects of dextroamphetamine, lithium chloride, sodium valproate and carbamazepine on intraplatelet Ca2+ levels.

Authors:  Michele L Ulrich; Susan Rotzinger; Sheila J Asghar; Paul Jurasz; Veronique A Tanay; Susan M J Dunn; Marek Radomski; Andy Greenshaw; Peter H Silverstone
Journal:  J Psychiatry Neurosci       Date:  2003-03       Impact factor: 6.186

2.  Factors affecting serotonin uptake into human platelets.

Authors:  E E Codd; T W McAllister; R F Walker
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

3.  2-Nitroimipramine: a photoaffinity probe for the serotonin uptake/tricyclic binding site complex.

Authors:  L P Wennogle; R A Ashton; D I Schuster; R B Murphy; L R Meyerson
Journal:  EMBO J       Date:  1985-04       Impact factor: 11.598
  3 in total

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