Literature DB >> 6310403

Priming for and induction of anti-poliovirus neutralizing antibodies by synthetic peptides.

E A Emini, B A Jameson, E Wimmer.   

Abstract

Five peptides containing amino acid sequences from the type 1 poliovirus structural protein VP1 have been synthesized. Each of the peptides was found capable of priming the immune system of rabbits for a long-lasting, virus-neutralizing IgG antibody response following a single inoculation of intact virus. One peptide directly induced the production of neutralizing antibody.

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Year:  1983        PMID： 6310403     DOI： 10.1038/304699a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  66 in total

1.  Mapping of B-cell epitopes on the polypeptide chain of the Epstein-Barr virus major envelope glycoprotein and candidate vaccine molecule gp340.

Authors:  R J Pither; C X Zhang; C Shiels; J Tarlton; S Finerty; A J Morgan
Journal:  J Virol       Date:  1992-02       Impact factor: 5.103

2.  Expression of the OSU rotavirus outer capsid protein VP4 by an adenovirus recombinant.

Authors:  M Gorziglia; A Z Kapikian
Journal:  J Virol       Date:  1992-07       Impact factor: 5.103

3.  Molecular basis for linkage of a continuous and discontinuous neutralization epitope on the structural polypeptide VP2 of poliovirus type 1.

Authors:  K J Wiegers; K Wetz; R Dernick
Journal:  J Virol       Date:  1990-03       Impact factor: 5.103

4.  Mutations conferring resistance to neutralization with monoclonal antibodies in type 1 poliovirus can be located outside or inside the antibody-binding site.

Authors:  B Blondel; R Crainic; O Fichot; G Dufraisse; A Candrea; D Diamond; M Girard; F Horaud
Journal:  J Virol       Date:  1986-01       Impact factor: 5.103

5.  Monoclonal antibodies: a potentially powerful tool in the diagnosis and treatment of infectious diseases.

Authors:  G Spira; R R Pollock; A Bargellesi; M D Scharff
Journal:  Eur J Clin Microbiol       Date:  1985-06       Impact factor: 3.267

Review 6.  New aspects of vaccine development.

Authors:  F Y Liew
Journal:  Clin Exp Immunol       Date:  1985-11       Impact factor: 4.330

7.  Location of the major antigenic sites involved in rotavirus serotype-specific neutralization.

Authors:  M L Dyall-Smith; I Lazdins; G W Tregear; I H Holmes
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

8.  Identification of group-common linear epitopes in structural and nonstructural proteins of enteroviruses by using synthetic peptides.

Authors:  J Cello; A Samuelson; P Stålhandske; B Svennerholm; S Jeansson; M Forsgren
Journal:  J Clin Microbiol       Date:  1993-04       Impact factor: 5.948

9.  Structural factors modulate the activity of antigenic poliovirus sequences expressed on hybrid hepatitis B surface antigen particles.

Authors:  F Delpeyroux; E Van Wezel; B Blondel; R Crainic
Journal:  J Virol       Date:  1990-12       Impact factor: 5.103

10.  The amino-terminal half of rotavirus SA114fM VP4 protein contains a hemagglutination domain and primes for neutralizing antibodies to the virus.

Authors:  M Lizano; S López; C F Arias
Journal:  J Virol       Date:  1991-03       Impact factor: 5.103
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