Literature DB >> 6309573

Effect of acclimation temperature on the concentration of the mitochondrial 'uncoupling' protein measured by radioimmunoassay in mouse brown adipose tissue.

M Ashwell, G Jennings, D Richard, D M Stirling, P Trayhurn.   

Abstract

The effect of acclimation temperature on the concentration of the mitochondrial 'uncoupling' protein (Mr 32000) from brown adipose tissue of mice has been investigated. The uncoupling protein was measured by a specific radioimmunoassay. Between 33 degrees C (thermoneutrality) and -2 degrees C there was a progressive increase with decreasing environmental temperature in the amount of uncoupling protein. For mice at -2 degrees C the mitochondrial concentration of the protein was 9-times higher than at 33 degrees C, while the total amount of the protein in interscapular brown adipose tissue was estimated to be nearly 80-times greater at -2 degrees C compared to 33 degrees C.

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Year:  1983        PMID： 6309573     DOI： 10.1016/0014-5793(83)80740-6

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  11 in total

1.  Functional atrophy of brown adipose tissue during lactation in mice. Effects of lactation and weaning on mitochondrial GDP binding and uncoupling protein.

Authors:  P Trayhurn; G Jennings
Journal:  Biochem J       Date:  1987-11-15       Impact factor: 3.857

2.  UCP1 is an essential mediator of the effects of methionine restriction on energy balance but not insulin sensitivity.

Authors:  Desiree Wanders; David H Burk; Cory C Cortez; Nancy T Van; Kirsten P Stone; Mollye Baker; Tamra Mendoza; Randall L Mynatt; Thomas W Gettys
Journal:  FASEB J       Date:  2015-03-05       Impact factor: 5.191

3.  Regulation of GDP binding and uncoupling-protein concentration in brown-adipose-tissue mitochondria. The effects of cold-acclimation, warm-reacclimation and noradrenaline.

Authors:  T Peachey; R R French; D A York
Journal:  Biochem J       Date:  1988-01-15       Impact factor: 3.857

4.  Cold-induced changes in brown adipose tissue thermogenic capacity of immunocompetent and immunodeficient hairless mice.

Authors:  J Houstĕk; M Holub
Journal:  J Comp Physiol B       Date:  1994       Impact factor: 2.200

5.  Brown adipose tissue activity in pyrexial cases of cot death.

Authors:  M E Lean; G Jennings
Journal:  J Clin Pathol       Date:  1989-11       Impact factor: 3.411

6.  Effect of photoperiod and acclimation temperature on nonshivering thermogenesis and GDP-binding of brown fat mitochondria in the Djungarian hamster Phodopus s. sungorus.

Authors:  H Wiesinger; G Heldmaier; A Buchberger
Journal:  Pflugers Arch       Date:  1989-04       Impact factor: 3.657

7.  The mitochondrial uncoupling protein from guinea-pig brown adipose tissue. Synchronous increase in structural and functional parameters during cold-adaptation.

Authors:  E Rial; D G Nicholls
Journal:  Biochem J       Date:  1984-09-15       Impact factor: 3.857

8.  Long photophase is not a sufficient stimulus to reduce thermogenic capacity in winter-acclimatized short-tailed field voles (Microtus agrestis) during long-term cold acclimation.

Authors:  R M McDevitt; J R Speakman
Journal:  J Comp Physiol B       Date:  1994       Impact factor: 2.200

9.  Brown adipose tissue dynamics in wild-type and UCP1-knockout mice: in vivo insights with magnetic resonance.

Authors:  Kirsten Grimpo; Maximilian N Völker; Eva N Heppe; Steve Braun; Johannes T Heverhagen; Gerhard Heldmaier
Journal:  J Lipid Res       Date:  2013-12-16       Impact factor: 5.922

10.  Cold exposure induces different uncoupling-protein thermogenin masking/unmasking processes in brown adipose tissue depending on mitochondrial subtypes.

Authors:  M Moreno; P Puigserver; J Llull; M Gianotti; A Lanni; F Goglia; A Palou
Journal:  Biochem J       Date:  1994-06-01       Impact factor: 3.857
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