Literature DB >> 6309000

Chromosome 3q (22-ter) encodes the human transferrin receptor.

Y E Miller, C Jones, C Scoggin, H Morse, P Seligman.   

Abstract

The human transferrin receptor is an integral membrane glycoprotein of 180,000 molecular weight (mol. wt.) formed from two subunits of 90,000 mol. wt. A clone panel of Chinese hamster-human somatic cell hybrids was screened using a single cell plating cytotoxicity assay and rabbit antiserum raised to purified human transferrin receptor. Chromosome 3 displayed the highest rate of concordance with the presence of human transferrin receptor, as assayed by cytotoxicity. Antitransferrin receptor serum-resistant segregants of chromosome 3 positive, receptor-positive hybrids were selected, using antiserum and complement. The segregants consistently lost chromosome 3. 125I human transferrin binding studies confirmed synteny between the functional human transferrin receptor and chromosome 3. Examination of hybrids with either translocated or deleted chromosome 3's allows regional mapping to 3q(22-ter).

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Year:  1983        PMID： 6309000      PMCID： PMC1685748     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  20 in total

1.  Isolation and characterization of the transferrin receptor from human placenta.

Authors:  P A Seligman; R B Schleicher; R H Allen
Journal:  J Biol Chem       Date:  1979-10-25       Impact factor: 5.157

2.  Identification of transferrin receptors on the surface of human cultured cells.

Authors:  T A Hamilton; H G Wada; H H Sussman
Journal:  Proc Natl Acad Sci U S A       Date:  1979-12       Impact factor: 11.205

3.  An abnormal membrane glycoprotein associated with malignancy in a wide range of different tumours.

Authors:  M E Bramwell; H Harris
Journal:  Proc R Soc Lond B Biol Sci       Date:  1978-04-13

4.  Similarities between the transferrin receptor proteins on human reticulocytes and human placentae.

Authors:  C A Enns; H H Sussman
Journal:  J Biol Chem       Date:  1981-12-25       Impact factor: 5.157

5.  Biosynthesis of the human transferrin receptor in cultured cells.

Authors:  M B Omary; I S Trowbridge
Journal:  J Biol Chem       Date:  1981-12-25       Impact factor: 5.157

6.  Simultaneous identification of chromatid replication and of human chromosomes in metaphases of man-mouse somatic cell hybrids. (With 1 color plate).

Authors:  B Alhadeff; M Velivasakis; M Siniscalco
Journal:  Cytogenet Cell Genet       Date:  1977

7.  Transferrin binding to peripheral blood lymphocytes activated by phytohemagglutinin involves a specific receptor. Ligand interaction.

Authors:  R M Galbraith; P Werner; P Arnaud; G M Galbraith
Journal:  J Clin Invest       Date:  1980-11       Impact factor: 14.808

8.  Hereditary hemochromatosis. Phenotypic expression of the disease.

Authors:  G E Cartwright; C Q Edwards; K Kravitz; M Skolnick; D B Amos; A Johnson; L Buskjaer
Journal:  N Engl J Med       Date:  1979-07-26       Impact factor: 91.245

9.  Demonstration, by somatic cell genetics, of coordinate regulation of genes for two enzymes of purine synthesis assigned to human chromosome 21.

Authors:  D Patterson; S Graw; C Jones
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205

10.  Chromosomal assignment of the gene for folylpolyglutamate synthetase to human chromosome 9.

Authors:  C Jones; F T Kao; R T Taylor
Journal:  Cytogenet Cell Genet       Date:  1980
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  12 in total

1.  Assignment of the gene for human sphingolipid activator protein-2 (SAP-2) to chromosome 10.

Authors:  S Fujibayashi; F T Kao; C Jones; H Morse; M Law; D A Wenger
Journal:  Am J Hum Genet       Date:  1985-07       Impact factor: 11.025

2.  Regional localization of chromosome 3-specific DNA fragments by using a hybrid cell deletion mapping panel.

Authors:  M J Gerber; H A Drabkin; C Firnhaber; Y E Miller; C H Scoggin; D I Smith
Journal:  Am J Hum Genet       Date:  1988-10       Impact factor: 11.025

3.  Identification of a cell-surface antigen produced by a gene on human chromosome 3 (cen-q22) and not expressed by Rhnull cells.

Authors:  Y E Miller; G L Daniels; C Jones; D K Palmer
Journal:  Am J Hum Genet       Date:  1987-12       Impact factor: 11.025

4.  Construction of single chain Fv antibody against transferrin receptor and its protein fusion with alkaline phosphatase.

Authors:  Dao-Feng Yang; Hui-Fen Zhu; Zhi-Hua Wang; Guan-Xin Shen; De-Ying Tian
Journal:  World J Gastroenterol       Date:  2005-06-07       Impact factor: 5.742

5.  Regional localization of the human transferrin receptor gene to 3q26.2----qter.

Authors:  M Rabin; A McClelland; L Kühn; F H Ruddle
Journal:  Am J Hum Genet       Date:  1985-11       Impact factor: 11.025

6.  The p97 antigen is mapped to the q24-qter region of chromosome 3; the same region as the transferrin receptor.

Authors:  P A Seligman; C D Butler; E J Massey; J A Kaur; J P Brown; G D Plowman; Y Miller; C Jones
Journal:  Am J Hum Genet       Date:  1986-04       Impact factor: 11.025

7.  HLA class I and H ferritin gene polymorphisms in normal subjects and patients with haemochromatosis.

Authors:  S J Cragg; C Darke; M Worwood
Journal:  Hum Genet       Date:  1988-09       Impact factor: 4.132

8.  Is soluble transferrin receptor a good marker of iron deficiency anemia in chronic kidney disease patients?

Authors:  S Gupta; B Uppal; B Pawar
Journal:  Indian J Nephrol       Date:  2009-07

9.  Human transferrin: cDNA characterization and chromosomal localization.

Authors:  F Yang; J B Lum; J R McGill; C M Moore; S L Naylor; P H van Bragt; W D Baldwin; B H Bowman
Journal:  Proc Natl Acad Sci U S A       Date:  1984-05       Impact factor: 11.205

10.  The gene coding for a sphingolipid activator protein, SAP-1, is on human chromosome 10.

Authors:  K Inui; F T Kao; S Fujibayashi; C Jones; H G Morse; M L Law; D A Wenger
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132
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