Literature DB >> 6308632

The carB gene of Escherichia coli: a duplicated gene coding for the large subunit of carbamoyl-phosphate synthetase.

H Nyunoya, C J Lusty.   

Abstract

Previous genetic and biochemical studies indicate that the carB gene of Escherichia coli codes for the large subunit of carbamoyl-phosphate synthetase (EC 6.3.5.5). We have determined the nucleotide sequence of a 4-kilobase-pair cloned fragment of E. coli DNA with genetic determinants for carB. The DNA sequence is a 3,219-nucleotide-long reading frame. The polypeptide encoded by this reading frame has been verified to be the large subunit of carbamoyl-phosphate synthetase. The gene product is similar to the large subunit in its molecular weight, amino acid composition and amino-terminal residue, and carboxyl-terminal sequence. The amino acid sequence derived from the nucleotide sequence shows a highly significant homology between the amino- and carboxyl-terminal halves of the protein. We propose that the carB gene was formed by an internal duplication of a smaller ancestral gene.

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Year:  1983        PMID： 6308632      PMCID： PMC384097          DOI： 10.1073/pnas.80.15.4629

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  22 in total

1.  Mechanism of the reaction catalyzed by carbamyl phosphate synthetase. Binding of ATP to the two functionally different ATP sites.

Authors:  S G Powers; A Meister
Journal:  J Biol Chem       Date:  1978-02-10       Impact factor: 5.157

Review 2.  Regulatory sequences involved in the promotion and termination of RNA transcription.

Authors:  M Rosenberg; D Court
Journal:  Annu Rev Genet       Date:  1979       Impact factor: 16.830

3.  Nucleotide sequence of the ribosomal protein gene cluster adjacent to the gene for RNA polymerase subunit beta in Escherichia coli.

Authors:  L E Post; G D Strycharz; M Nomura; H Lewis; P P Dennis
Journal:  Proc Natl Acad Sci U S A       Date:  1979-04       Impact factor: 11.205

4.  The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes.

Authors:  D A Konkel; J V Maizel; P Leder
Journal:  Cell       Date:  1979-11       Impact factor: 41.582

5.  Use of gene cloning to determine polarity of an operon: genes carAB of Escherichia coli.

Authors:  M Crabeel; D Charlier; G Weyens; A Feller; A Piérard; N Glansdorff
Journal:  J Bacteriol       Date:  1980-08       Impact factor: 3.490

6.  Covalent modification of the active site of carbamyl phosphate synthetase by 5'-p-fluorosulfonylbenzoyladenosine. Direct evidence for two functionally different ATP-binding sites.

Authors:  B R Boettcher; A Meister
Journal:  J Biol Chem       Date:  1980-08-10       Impact factor: 5.157

7.  In vitro synthesis of Escherichia coli carbamoylphosphate synthase: evidence for participation of the arginine repressor in cumulative repression.

Authors:  W Lissens; R Cunin; N Kelker; N Glansdorff; A Piérard
Journal:  J Bacteriol       Date:  1980-01       Impact factor: 3.490

8.  Sequencing end-labeled DNA with base-specific chemical cleavages.

Authors:  A M Maxam; W Gilbert
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

9.  Patterns of polarity in the Escherichia coli car AB gene cluster.

Authors:  D Gigot; M Crabeel; A Feller; D Charlier; W Lissens; N Glansdorff; A Piérard
Journal:  J Bacteriol       Date:  1980-08       Impact factor: 3.490

10.  Binding of allosteric effectors to carbamyl-phosphate synthetase from Escherichia coli.

Authors:  P M Anderson
Journal:  Biochemistry       Date:  1977-02-22       Impact factor: 3.162
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  43 in total

Review 1.  Structure, function and regulation of pyruvate carboxylase.

Authors:  S Jitrapakdee; J C Wallace
Journal:  Biochem J       Date:  1999-05-15       Impact factor: 3.857

2.  Nucleotide recognition in the ATP-grasp protein carbamoyl phosphate synthetase.

Authors:  Michael Kothe; Susan G Powers-Lee
Journal:  Protein Sci       Date:  2004-01-10       Impact factor: 6.725

3.  Ancient gene duplications and the root(s) of the tree of life.

Authors:  Olga Zhaxybayeva; Pascal Lapierre; J Peter Gogarten
Journal:  Protoplasma       Date:  2005-12-30       Impact factor: 3.356

4.  Acetyl-CoA carboxylase from Escherichia coli: gene organization and nucleotide sequence of the biotin carboxylase subunit.

Authors:  H Kondo; K Shiratsuchi; T Yoshimoto; T Masuda; A Kitazono; D Tsuru; M Anai; M Sekiguchi; T Tanabe
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-01       Impact factor: 11.205

Review 5.  Linkage map of Escherichia coli K-12, edition 10: the traditional map.

Authors:  M K Berlyn
Journal:  Microbiol Mol Biol Rev       Date:  1998-09       Impact factor: 11.056

Review 6.  Linkage map of Escherichia coli K-12, edition 8.

Authors:  B J Bachmann
Journal:  Microbiol Rev       Date:  1990-06

Review 7.  Archaea and the prokaryote-to-eukaryote transition.

Authors:  J R Brown; W F Doolittle
Journal:  Microbiol Mol Biol Rev       Date:  1997-12       Impact factor: 11.056

8.  Gene sequence encoding early enzymes of arginine synthesis within a cluster in Bacillus subtilis, as revealed by cloning in Escherichia coli.

Authors:  A Mountain; J McChesney; M C Smith; S Baumberg
Journal:  J Bacteriol       Date:  1986-03       Impact factor: 3.490

9.  Molecular analysis of the Trichosporon cutaneum DSM 70698 argA gene and its use for DNA-mediated transformations.

Authors:  J Reiser; V Glumoff; U A Ochsner; A Fiechter
Journal:  J Bacteriol       Date:  1994-05       Impact factor: 3.490

10.  Human carbamoyl-phosphate synthetase: insight into N-acetylglutamate interaction and the functional effects of a common single nucleotide polymorphism.

Authors:  V Ahuja; S G Powers-Lee
Journal:  J Inherit Metab Dis       Date:  2008-08-09       Impact factor: 4.982
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