Literature DB >> 6308594

Epidermal growth factor receptors on isolated human placental syncytiotrophoblast plasma membrane.

R C Richards, J M Beardmore, P J Brown, C M Molloy, P M Johnson.   

Abstract

Receptor sites for mEGF that are specific, saturable and reversible have been demonstrated on isolated syncytiotrophoblast microvillous plasma membrane from term human placentae. Analysis of the binding data indicated the presence of two receptor populations. The high affinity population had 1.7 X 10(13) sites per mg membrane protein with an affinity constant (Ka) of 5.4 X 10(9)/M. The receptors of lower affinity had a Ka of 4.1 X 10(8)/M and 3.1 X 10(13) sites per mg membrane protein.

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Year:  1983        PMID: 6308594     DOI: 10.1016/s0143-4004(83)80026-5

Source DB:  PubMed          Journal:  Placenta        ISSN: 0143-4004            Impact factor:   3.481


  4 in total

1.  A Cross-Linking-Aided Immunoprecipitation/Mass Spectrometry Workflow Reveals Extensive Intracellular Trafficking in Time-Resolved, Signal-Dependent Epidermal Growth Factor Receptor Proteome.

Authors:  Yue Chen; Mei Leng; Yankun Gao; Dongdong Zhan; Jong Min Choi; Lei Song; Kai Li; Xia Xia; Chunchao Zhang; Mingwei Liu; Shuhui Ji; Antrix Jain; Alexander B Saltzman; Anna Malovannaya; Jun Qin; Sung Yun Jung; Yi Wang
Journal:  J Proteome Res       Date:  2019-09-09       Impact factor: 4.466

2.  Functional receptors for epidermal growth factor in an epithelial-cell line derived from the rat small intestine.

Authors:  J Blay; K D Brown
Journal:  Biochem J       Date:  1985-01-01       Impact factor: 3.857

3.  Polysialic acid enhances the migration and invasion of human cytotrophoblasts.

Authors:  Bethann S Hromatka; Penelope M Drake; Mirhan Kapidzic; Haley Stolp; Gabriel A Goldfien; Ie-Ming Shih; Susan J Fisher
Journal:  Glycobiology       Date:  2012-12-03       Impact factor: 4.313

4.  The effects of intracolonic EGF on mucosal growth and experimental carcinogenesis.

Authors:  J R Reeves; R C Richards; T Cooke
Journal:  Br J Cancer       Date:  1991-02       Impact factor: 7.640

  4 in total

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