Literature DB >> 6308352

A small animal model study of perlite and fir bark dust on guinea pig lungs.

R F McMichael, J R DiPalma, R Blumenstein, P S Amenta, A P Freedman, E J Barbieri.   

Abstract

Fir bark (Abies) and perlite (noncrystalline silicate) dusts have been reported to cause pulmonary disease in humans. Guinea pigs were exposed to either fir bark or perlite dust in a special chamber. Severe pathologic changes occurred in the lungs, consisting of lymphoid aggregated and a perivascular inflammatory response. Both dusts caused similar changes although one was vegetable (fir bark) and the other mineral (perlite). Fir bark and perlite dust appeared to be more than just nuisance dusts.

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Year:  1983        PMID: 6308352     DOI: 10.1016/0160-5402(83)90040-2

Source DB:  PubMed          Journal:  J Pharmacol Methods        ISSN: 0160-5402


  2 in total

1.  Respiratory disease related mortality and morbidity on an island of Greece exposed to perlite and bentonite mining dust.

Authors:  Stefanos Sampatakakis; Athena Linos; Eleni Papadimitriou; Athanasios Petralias; Archontoula Dalma; Eirini Saranti Papasaranti; Eleni Christoforidou; Melina Stoltidis
Journal:  Int J Environ Res Public Health       Date:  2013-10-14       Impact factor: 3.390

Review 2.  Perlite toxicology and epidemiology--a review.

Authors:  L Daniel Maxim; Ron Niebo; Ernest E McConnell
Journal:  Inhal Toxicol       Date:  2014-03-07       Impact factor: 2.724

  2 in total

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