Literature DB >> 630711

Quantitation of anticonvulsant drugs in serum by gas-chromatography on the stationary phase SP-2510.

W Godolphin, J Thoma.   

Abstract

A new column packing, SP-2510 DA (Supelco, Inc., Bellefonte, Pa. 16823), is an excellent stationary phase for the determination of a wide variety of anticonvulsant drugs by gas--liquid chromatography without derivatization. However, when uncomplicated extraction procedures are used, serum cholesterol interferes with the determination of primidone. By the simple expedient of adding a short "pre-column" containing another phase (SP-2250 DA) the problem is overcome.

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Year:  1978        PMID: 630711

Source DB:  PubMed          Journal:  Clin Chem        ISSN: 0009-9147            Impact factor:   8.327


  2 in total

1.  Positive and negative ion mass spectrometry of antiepileptic hydantoins and their analogs.

Authors:  Y Ishikawa; O Suzuki; H Hattori; T Kumazawa; T Takahashi
Journal:  Z Rechtsmed       Date:  1988

2.  Rapid isolation of some antiepileptic hydantoins and their analogues with Sep-Pak C18 cartridges and capillary gas chromatography with splitless injection.

Authors:  T Kumazawa; O Suzuki; H Seno; Y Ishikawa; H Hattori
Journal:  Z Rechtsmed       Date:  1990
  2 in total

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