Literature DB >> 6306391

Metabolic abnormalities in diabetic peripheral nerve: relation to impaired function.

D A Greene.   

Abstract

An hypothesis is presented relating several well-defined metabolic abnormalities in diabetic peripheral nerve to impaired peripheral nerve function by a sodium-potassium ATPase mechanism. It is proposed that this hypothesis be tested in the most well-defined animal model for human insulin deficiency diabetes currently available--the BB diabetic rat.

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Year:  1983        PMID: 6306391     DOI: 10.1016/s0026-0495(83)80024-9

Source DB:  PubMed          Journal:  Metabolism        ISSN: 0026-0495            Impact factor:   8.694


  14 in total

1.  A note on the mechanism of resistance to anoxia and ischaemia in pathophysiological mammalian myelinated nerve.

Authors:  J M Ritchie
Journal:  J Neurol Neurosurg Psychiatry       Date:  1985-03       Impact factor: 10.154

2.  Histopathological heterogeneity of neuropathy in insulin-dependent and non-insulin-dependent diabetes, and demonstration of axo-glial dysjunction in human diabetic neuropathy.

Authors:  A A Sima; V Nathaniel; V Bril; T A McEwen; D A Greene
Journal:  J Clin Invest       Date:  1988-02       Impact factor: 14.808

3.  Restoration of ultrastructural and biochemical changes in alloxan-induced diabetic rat sciatic nerve on treatment with Na3VO4 and Trigonella--a promising antidiabetic agent.

Authors:  Anju Preet; Bihari L Gupta; Mohamed R Siddiqui; Pramod K Yadava; Nazma Zaheer Baquer
Journal:  Mol Cell Biochem       Date:  2005-10       Impact factor: 3.396

4.  Susceptibility to diabetic neuropathy in patients with insulin dependent diabetes mellitus is associated with a polymorphism at the 5' end of the aldose reductase gene.

Authors:  A E Heesom; A Millward; A G Demaine
Journal:  J Neurol Neurosurg Psychiatry       Date:  1998-02       Impact factor: 10.154

5.  Aminoguanidine effects on nerve blood flow, vascular permeability, electrophysiology, and oxygen free radicals.

Authors:  M Kihara; J D Schmelzer; J F Poduslo; G L Curran; K K Nickander; P A Low
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-15       Impact factor: 11.205

Review 6.  Sorbitol, myo-inositol and sodium-potassium ATPase in diabetic peripheral nerve.

Authors:  D A Greene
Journal:  Drugs       Date:  1986       Impact factor: 9.546

7.  Axo-glial dysjunction. A novel structural lesion that accounts for poorly reversible slowing of nerve conduction in the spontaneously diabetic bio-breeding rat.

Authors:  A A Sima; S A Lattimer; S Yagihashi; D A Greene
Journal:  J Clin Invest       Date:  1986-02       Impact factor: 14.808

8.  Peripheral nerve function in relation to quality of metabolic control in diabetes.

Authors:  F W Bertelsmann; J J Heimans; J C van Rooy; C Popp-Snijders; E A van der Veen
Journal:  J Neurol       Date:  1987-06       Impact factor: 4.849

9.  Experimental diabetic neuropathy: impairment of slow transport with changes in axon cross-sectional area.

Authors:  R Medori; L Autilio-Gambetti; S Monaco; P Gambetti
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205

10.  Cardiac sympathetic tone in anaesthetized diabetics.

Authors:  K Tsueda; K C Huang; S W Dumont; T J Wieman; M H Thomas; M F Heine
Journal:  Can J Anaesth       Date:  1991-01       Impact factor: 5.063

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