| Literature DB >> 6306251 |
Abstract
The antibiotic netropsin binds to DNA by a non-intercalative mechanism. It increases the linking number of DNA so that in the presence of topoisomerase I, positively supercoiled molecules are produced.Mesh:
Substances:
Year: 1983 PMID: 6306251 DOI: 10.1016/s0022-2836(83)80043-6
Source DB: PubMed Journal: J Mol Biol ISSN: 0022-2836 Impact factor: 5.469