Literature DB >> 6305834

Effects of leukocyte inhibitory factor (LIF) on human neutrophil function.

M S Klempner, R E Rocklin.   

Abstract

The effects of the lymphokine, leukocyte inhibitory factor (LIF), on human neutrophil function were studied. This soluble mediator, which is defined by its specific inhibition of neutrophil locomotion, does not interfere with chemotactic factor binding and does not affect basal or stimulated superoxide generation by neutrophils. In contrast, phagocytosis of opsonized Staphylococcus aureus is markedly inhibited by LIF, and degranulation is stimulated by this lymphokine. The possible mechanisms of LIF action on neutrophils are discussed.

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Year:  1983        PMID: 6305834     DOI: 10.1007/bf00917819

Source DB:  PubMed          Journal:  Inflammation        ISSN: 0360-3997            Impact factor:   4.092


  26 in total

1.  STUDIES ON THE PATHOGENESIS OF ACUTE INFLAMMATION. V. AN ASSESSMENT OF FACTORS THAT INFLUENCE IN VITRO THE PHAGOCYTIC AND ADHESIVE PROPERTIES OF LEUKOCYTES OBTAINED FROM RABBIT PERITONEAL EXUDATE.

Authors:  F ALLISON; M G LANCASTER; J L CROSTHWAITE
Journal:  Am J Pathol       Date:  1963-11       Impact factor: 4.307

2.  Cyclic GMP and cell movement.

Authors:  R D Estensen; H R Hill; P G Quie; N Gogan; N D Goldberg
Journal:  Nature       Date:  1973-10-26       Impact factor: 49.962

3.  Stimulation of neutrophil oxidative metabolism by chemotactic peptides: influence of calcium ion concentration and cytochalasin B and comparison with stimulation by phorbol myristate acetate.

Authors:  J E Lehmeyer; R Snyderman; R B Johnston
Journal:  Blood       Date:  1979-07       Impact factor: 22.113

4.  Calcium-induced lysozyme secretion from human polymorphonuclear leukocytes.

Authors:  I M Goldstein; J K Horn; H B Kaplan; G Weissmann
Journal:  Biochem Biophys Res Commun       Date:  1974-09-23       Impact factor: 3.575

5.  Lysosomal enzyme release from human leukocytes: mediation by the alternate pathway of complement activation.

Authors:  I M Goldstein; M Brai; A G Osler; G Weissmann
Journal:  J Immunol       Date:  1973-07       Impact factor: 5.422

6.  Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

Authors:  A Böyum
Journal:  Scand J Clin Lab Invest Suppl       Date:  1968

7.  Effects of cytochalasin B on polymorphonuclear leucocyte locomotion, phagocytosis and glycolysis.

Authors:  S H Zigmond; J G Hirsch
Journal:  Exp Cell Res       Date:  1972-08       Impact factor: 3.905

8.  Control of cytoplasmic actin gel-sol transformation by gelsolin, a calcium-dependent regulatory protein.

Authors:  H L Yin; T P Stossel
Journal:  Nature       Date:  1979-10-18       Impact factor: 49.962

9.  Separation and functional characterization of human neutrophil subpopulations.

Authors:  M S Klempner; J I Gallin
Journal:  Blood       Date:  1978-04       Impact factor: 22.113

10.  Specific binding of leukocyte inhibitory factor to neutrophil plasma membranes.

Authors:  M S Klempner; R E Rocklin
Journal:  J Immunol       Date:  1982-05       Impact factor: 5.422

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  6 in total

1.  Potentiation of neutrophil aggregation by human leukocyte inhibitory factor.

Authors:  H Schainberg; L Borish; R E Rocklin
Journal:  Inflammation       Date:  1988-06       Impact factor: 4.092

2.  Conditioned medium from stimulated mononuclear leukocytes augments human neutrophil-mediated killing of a virulent Acanthamoeba sp.

Authors:  A Ferrante; T J Abell
Journal:  Infect Immun       Date:  1986-02       Impact factor: 3.441

3.  Inhibition of neutrophil superoxide production by fanetizole.

Authors:  B Styrt; R E Rocklin; M S Klempner
Journal:  Inflammation       Date:  1985-09       Impact factor: 4.092

4.  Staphylococcus aureus-stimulated human mononuclear leucocyte-conditioned medium augments the basal and stimuli-induced neutrophil respiratory burst and degranulation.

Authors:  A Ferrante; M Nandoskar; E J Bates; D H Goh
Journal:  Immunology       Date:  1987-03       Impact factor: 7.397

5.  Endotoxin inhalation induces neutrophil chemotaxis by alveolar macrophages.

Authors:  M C Snella; R Rylander
Journal:  Agents Actions       Date:  1985-09

6.  The role of caspase-1, caspase-4 and NLRP3 in regulating the host cell response evoked by uropathogenic Escherichia coli.

Authors:  Anna Lindblad; Charlotte Johansson; Katarina Persson; Isak Demirel
Journal:  Sci Rep       Date:  2022-02-07       Impact factor: 4.379

  6 in total

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