Literature DB >> 6305716

Superoxide-dependent formation of hydroxyl radical catalyzed by transferrin.

N Motohashi, I Mori.   

Abstract

Hydroxyl radicals are generated in the hypoxanthine-xanthine oxidase system in the presence of iron-saturated transferrin isolated from human serum. This has been demonstrated by colorimetrically measuring the hydroxylation of salicylic acid and by EPR using the spin trap DMPO (5,5-dimethyl-1-pyrroline-N-oxide). A Fenton-type Harber-Weiss reaction catalyzed by transferrin is proposed.

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Year:  1983        PMID： 6305716     DOI： 10.1016/0014-5793(83)81144-2

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  10 in total

1.  1018 - ACTIVATION OF OXYGEN BY METAL COMPLEXES AND ITS RELEVANCE TO AUTOXIDATIVE PROCESSES IN LIVING SYSTEMS.

Authors:  Garry R Buettner
Journal:  J Electroanal Chem Interfacial Electrochem       Date:  1987-12-01

Review 2.  Oxygen toxicity, oxygen radicals, transition metals and disease.

Authors:  B Halliwell; J M Gutteridge
Journal:  Biochem J       Date:  1984-04-01       Impact factor: 3.857

3.  Superoxide-dependent and ascorbate-dependent formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Are lactoferrin and transferrin promoters of hydroxyl-radical generation?

Authors:  O I Aruoma; B Halliwell
Journal:  Biochem J       Date:  1987-01-01       Impact factor: 3.857

4.  Iron mobilization from ferritin by superoxide derived from stimulated polymorphonuclear leukocytes. Possible mechanism in inflammation diseases.

Authors:  P Biemond; H G van Eijk; A J Swaak; J F Koster
Journal:  J Clin Invest       Date:  1984-06       Impact factor: 14.808

5.  Pseudomonas and neutrophil products modify transferrin and lactoferrin to create conditions that favor hydroxyl radical formation.

Authors:  B E Britigan; B L Edeker
Journal:  J Clin Invest       Date:  1991-10       Impact factor: 14.808

6.  Mass spectrometric characterization of transferrins and their fragments derived by reduction of disulfide bonds.

Authors:  Mario Thevis; Rachel R Ogorzalek Loo; Joseph A Loo
Journal:  J Am Soc Mass Spectrom       Date:  2003-06       Impact factor: 3.109

7.  Crocetin reduces the oxidative stress induced reactive oxygen species in the stroke-prone spontaneously hypertensive rats (SHRSPs) brain.

Authors:  Fumihiko Yoshino; Ayaka Yoshida; Naofumi Umigai; Koya Kubo; Masaichi-Chang-Il Lee
Journal:  J Clin Biochem Nutr       Date:  2011-10-29       Impact factor: 3.114

8.  Prooxidant activity of transferrin and lactoferrin.

Authors:  S J Klebanoff; A M Waltersdorph
Journal:  J Exp Med       Date:  1990-11-01       Impact factor: 14.307

Review 9.  The role of oxygen free radicals in occupational and environmental lung diseases.

Authors:  V Vallyathan; X Shi
Journal:  Environ Health Perspect       Date:  1997-02       Impact factor: 9.031

10.  Production of oxygen-centered radicals by neutrophils and macrophages as studied by electron spin resonance (ESR).

Authors:  J V Bannister; W H Bannister
Journal:  Environ Health Perspect       Date:  1985-12       Impact factor: 9.031
  10 in total

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