Literature DB >> 6304816

Heterogeneity of leukotriene receptors in guinea-pig trachea.

R D Krell, B S Tsai, A Berdoulay, M Barone, R E Giles.   

Abstract

The selective leukotriene (LT) antagonist FPL 55712 antagonized the contractile activity of synthetic LTD4 and E4 on guinea-pig trachea. Schild analysis of the antagonism provided evidence for two distinct receptors for LTD4: one with significantly higher affinity for FPL 55712 than the other. LTE4 appears to interact preferentially with the high affinity receptor.

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Year:  1983        PMID： 6304816     DOI： 10.1016/0090-6980(83)90102-8

Source DB:  PubMed          Journal:  Prostaglandins        ISSN： 0090-6980


  11 in total

Review 1.  Leukotriene receptors.

Authors:  S E Dahlén
Journal:  Clin Rev Allergy Immunol       Date:  1999 Spring-Summer       Impact factor: 8.667

2.  SK&F S-106203 inhibits leukotriene C4, leukotriene D4 and leukotriene E4 vasopressor responses in the conscious rat.

Authors:  E F Smith; M J Slivjak; J W Egan; R D Eckardt; J F Newton
Journal:  Br J Pharmacol       Date:  1990-06       Impact factor: 8.739

3.  Antigen-induced contraction of guinea-pig isolated trachea: studies with novel inhibitors and antagonists of arachidonic acid metabolites.

Authors:  T R Jones; L Charette; D Denis
Journal:  Br J Pharmacol       Date:  1988-09       Impact factor: 8.739

4.  An alternative pathway for metabolism of leukotriene D(4): effects on contractions to cysteinyl-leukotrienes in the guinea-pig trachea.

Authors:  M Bäck; M Kumlin; I A Cotgreave; S E Dahlén
Journal:  Br J Pharmacol       Date:  2001-08       Impact factor: 8.739

5.  Evaluation of LY163443, 1-[2-hydroxy-3-propyl-4-([4- (1H-tetrazol-5-ylmethyl)phenoxy]methyl) phenyl]ethanone, as a pharmacologic antagonist of leukotrienes D4 and E4.

Authors:  J H Fleisch; L E Rinkema; K D Haisch; D McCullough; F P Carr; R D Dillard
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-05       Impact factor: 3.000

Review 6.  Leukotriene receptors as potential therapeutic targets.

Authors:  Takehiko Yokomizo; Motonao Nakamura; Takao Shimizu
Journal:  J Clin Invest       Date:  2018-05-14       Impact factor: 14.808

7.  Characterization of a leukotriene D4 receptor in guinea pig lung.

Authors:  S S Pong; R N DeHaven
Journal:  Proc Natl Acad Sci U S A       Date:  1983-12       Impact factor: 11.205

8.  Leukotriene D4 receptors are not negatively coupled to adenylyl cyclase in guinea-pig lung parenchyma.

Authors:  M A Giembycz; J Diamond; I W Rodger
Journal:  Br J Pharmacol       Date:  1993-03       Impact factor: 8.739

9.  The contractile activities of lipoxin A4 and lipoxin B4 for guinea-pig airway tissues.

Authors:  C A Jacques; B W Spur; A E Crea; T H Lee
Journal:  Br J Pharmacol       Date:  1988-10       Impact factor: 8.739

10.  Leukotriene receptors on human pulmonary vascular endothelium.

Authors:  J L Ortiz; I Gorenne; J Cortijo; A Seller; C Labat; B Sarria; T S Abram; P J Gardiner; E Morcillo; C Brink
Journal:  Br J Pharmacol       Date:  1995-08       Impact factor: 8.739
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