Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Expression of HLA-DR antigens at the surface of mouse L cells co-transfected with cloned human genes.

Literature DB >> 6304534

Expression of HLA-DR antigens at the surface of mouse L cells co-transfected with cloned human genes.

Abstract

The H-2 I region in the mouse and the HLA-D region in humans contain a set of polymorphic genes which encode Ia antigens and control the immune response. Cloned genes for the different polypeptide chains of one of the human Ia antigens, HLA-DR, have been used for the co-transformation of mouse L cells. Expression of HLA-DR antigens at the surface of transfected mouse cells has been documented with monoclonal antibodies.

Entities: Species

Mesh：

Substances：

Year: 1983 PMID： 6304534 DOI： 10.1038/303670a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

Keyword Cloud
Cited

20 in total

1. Serological recognition of HLA-DR allodeterminant corresponding to DNA sequence involved in gene conversion.

Authors: C C Berte; N Tanigaki; R Tosi; J Gorski; B Mach
Journal: Immunogenetics Date: 1988 Impact factor: 2.846

2. Antigen presentation to HLA class II-restricted measles virus-specific T-cell clones can occur in the absence of the invariant chain.

Authors: R P Sekaly; S Jacobson; J R Richert; C Tonnelle; H F McFarland; E O Long
Journal: Proc Natl Acad Sci U S A Date: 1988-02 Impact factor: 11.205

3. The role of transfected HLA-DQ genes in the mixed lymphocyte reaction-like condition.

Authors: T Nakatsuji; H Inoko; A Ando; T Sato; Y Koide; T Tadakuma; T O Yoshida; K Tsuji
Journal: Immunogenetics Date: 1987 Impact factor: 2.846

4. Characterization of N-linked oligosaccharides of an HLA-DR molecule expressed in different cell lines.

Authors: D Néel; B Merlu; E Turpin; C Rabourdin-Combe; B Mach; Y Goussault; D J Charron
Journal: Biochem J Date: 1987-06-01 Impact factor: 3.857

5. Immunochemistry of the HLA class II molecules isolated from a mouse cell transfected with DQ alpha and beta genes from a DR4 haplotype.

Authors: N Tanigaki; R Tosi; J L Strominger; J Cooper
Journal: Immunogenetics Date: 1987 Impact factor: 2.846

6. Structure and expression of HLA-DQ alpha and -DX alpha genes: interallelic alternate splicing of the HLA-DQ alpha gene and functional splicing of the HLA-DQ alpha gene using a retroviral vector.

Authors: C Auffray; J W Lillie; A J Korman; J M Boss; N Fréchin; F Guillemot; J Cooper; R C Mulligan; J L Strominger
Journal: Immunogenetics Date: 1987 Impact factor: 2.846

Expression of HLA-DR antigens at the surface of mouse L cells co-transfected with cloned human genes.

1. Serological recognition of HLA-DR allodeterminant corresponding to DNA sequence involved in gene conversion.

2. Antigen presentation to HLA class II-restricted measles virus-specific T-cell clones can occur in the absence of the invariant chain.

3. The role of transfected HLA-DQ genes in the mixed lymphocyte reaction-like condition.

4. Characterization of N-linked oligosaccharides of an HLA-DR molecule expressed in different cell lines.

5. Immunochemistry of the HLA class II molecules isolated from a mouse cell transfected with DQ alpha and beta genes from a DR4 haplotype.

6. Structure and expression of HLA-DQ alpha and -DX alpha genes: interallelic alternate splicing of the HLA-DQ alpha gene and functional splicing of the HLA-DQ alpha gene using a retroviral vector.

7. Linkage map of three HLA-DR beta-chain genes: evidence for a recent duplication event.

8. Ia-transfected L-cell fibroblasts present a lysozyme peptide but not the native protein to lysozyme-specific T cells.

Review 9. In search of a function for the invariant chain associated with Ia antigens.

10. Isolation of cDNA clones for the p33 invariant chain associated with HLA-DR antigens.