| Literature DB >> 6303950 |
Abstract
Two herpes simplex virus type 1 (HSV-1) antigens of apparent molecular weight 123,000 and 63,000 which are associated with the viral glycoprotein complex have been identified and purified using virus-specific monoclonal antibodies. Mice immunized with either glycoprotein showed marked resistance to challenge with virulent HSV-1. Therefore purified glycoproteins of HSV-1 free of nucleic acid can be used in protective immunization of mice against human herpes simplex type 1.Entities:
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Year: 1983 PMID: 6303950 PMCID: PMC1454196
Source DB: PubMed Journal: Immunology ISSN: 0019-2805 Impact factor: 7.397