Literature DB >> 6303832

The effect of a gastric mucus barrier on the dynamic response of a pH electrode.

P Vadgama, K G Alberti.   

Abstract

Hydrogen ion mobility in gastric mucus has been found to be reduced to a greater extent than that hitherto suspected, though at low pH (less than 4) and in buffer this mobility increases. Mucus, at an optimized pH, may therefore protect the gastric mucosa from acid digestion by providing a diffusion barrier.

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Year:  1983        PMID： 6303832     DOI： 10.1007/bf01971102

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  Mucosubstance as a barrier to diffusion.

Authors:  N G HEATLEY
Journal:  Gastroenterology       Date:  1959-09       Impact factor: 22.682

2.  Buffer-facilitated proton transport. pH profile of bound enzymes.

Authors:  J M Engasser; C Horvath
Journal:  Biochim Biophys Acta       Date:  1974-07-17

3.  Fourier analysis of the transient response of potentiometric enzyme electrodes.

Authors:  P W Carr
Journal:  Anal Chem       Date:  1977-05       Impact factor: 6.986

4.  Experimental analysis of hydrogen ion diffusion in gastrointestinal mucus glycoprotein.

Authors:  C J Pfeiffer
Journal:  Am J Physiol       Date:  1981-02

5.  Demonstration of a pH gradient across the mucus layer on the surface of human gastric mucosa in vitro.

Authors:  H M Bahari; I N Ross; L A Turnberg
Journal:  Gut       Date:  1982-06       Impact factor: 23.059

Review 6.  Mucus and bicarbonate secretion in the stomach and their possible role in mucosal protection.

Authors:  A Allen; A Garner
Journal:  Gut       Date:  1980-03       Impact factor: 23.059

7.  Demonstration of a pH gradient across mucus adherent to rabbit gastric mucosa: evidence for a 'mucus-bicarbonate' barrier.

Authors:  S E Williams; L A Turnberg
Journal:  Gut       Date:  1981-02       Impact factor: 23.059

8.  Retardation of acid diffusion by pig gastric mucosa: a potential role in mucosal protection.

Authors:  S E Williams; L A Turnberg
Journal:  Gastroenterology       Date:  1980-08       Impact factor: 22.682

9.  A quantitative statement of the two-component hypothesis of gastric secretion.

Authors:  G M Makhlouf; J P McManus; W I Card
Journal:  Gastroenterology       Date:  1966-08       Impact factor: 22.682

10.  The pH gradient across mucus adherent to rat fundic mucosa in vivo and the effect of potential damaging agents.

Authors:  I N Ross; H M Bahari; L A Turnberg
Journal:  Gastroenterology       Date:  1981-10       Impact factor: 22.682
  10 in total

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