Literature DB >> 6303809

Regional distribution of [3H]imipramine binding sites in the CNS of Roman high and low avoidance rats.

C Gentsch, M Lichtsteiner, H Feer.   

Abstract

The high affinity binding of [3H]imipramine to membranes was compared in 7 brain regions from two psychogenetically selected rat lines (RHA/Verh, RLA/Verh). A significantly higher binding in RHA/Verh rats, as compared to RLA/Verh rats, was found in cortex and striatum. All other regions, except hypothalamus, showed a trend in the same direction (RHA/Verh greater than RLA/Verh). In the hypothalamus, however, [3H]imipramine binding for RLA/Verh rats significantly exceeded that found in RHA/Verh animals.

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Year:  1983        PMID： 6303809     DOI： 10.1016/0014-2999(83)90015-8

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  5 in total

Review 1.  Using genetically-defined rodent strains for the identification of hippocampal traits relevant for two-way avoidance behavior: a non-invasive approach.

Authors:  H P Lipp; H Schwegler; W E Crusio; D P Wolfer; M C Leisinger-Trigona; B Heimrich; P Driscoll
Journal:  Experientia       Date:  1989-09-15

2.  Roman high- and low-avoidance rats: present status of the Swiss sublines, RHA/Verh and RLA/Verh, and effects of amphetamine on shuttle-box performance.

Authors:  P Driscoll
Journal:  Behav Genet       Date:  1986-05       Impact factor: 2.805

3.  Cerebral tryptophan hydroxylase activity, and 5-HT1A receptor, 5-HT2A receptor, and 5-HT transporter binding in grouped and isolated Roman RHA and RLA rats: relationships with behaviours in two models of anxiety.

Authors:  A Kulikov; N Castanon; P Mormède; F Chaouloff
Journal:  Psychopharmacology (Berl)       Date:  1995-10       Impact factor: 4.530

4.  Differential response to cholinergic stimulation in psychogenitically selected rat lines.

Authors:  J R Martin; P Driscoll; C Gentsch
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

Review 5.  Genetic and environmental influences on behavioral and neurochemical aspects of emotionality in rats.

Authors:  C Gentsch; M Lichtsteiner; H Feer
Journal:  Experientia       Date:  1988-06-15
  5 in total

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