Literature DB >> 6302635

Tonic and phasic INa blockade by antiarrhythmics. Different properties of drug binding to fast sodium channels as judged from Vmax studies with propafenone and derivatives in mammalian ventricular myocardium.

M Kohlhardt, C Seifert, L M Hondeghem.   

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Year:  1983        PMID： 6302635     DOI： 10.1007/bf00587856

Source DB:  PubMed          Journal:  Pflugers Arch        ISSN： 0031-6768            Impact factor:   3.657


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  26 in total

1.  Effects of calcium ions and local anesthetics on electrical properties of Purkinje fibres.

Authors:  S WEIDMANN
Journal:  J Physiol       Date:  1955-09-28       Impact factor: 5.182

2.  Effect of lidocaine and quinidine on steady-state characteristics and recovery kinetics of (dV/dt)max in guinea pig ventricular myocardium.

Authors:  C M Chen; L S Gettes; B G Katzung
Journal:  Circ Res       Date:  1975-07       Impact factor: 17.367

Review 3.  Ionic mechanisms in heart muscle in relation to the genesis and the pharmacological control of cardiac arrhythmias.

Authors:  O Hauswirth; B N Singh
Journal:  Pharmacol Rev       Date:  1978-03       Impact factor: 25.468

Review 4.  Sodium inactivation and drug-induced immobilization of the gating charge in nerve membrane.

Authors:  B I Khodorov
Journal:  Prog Biophys Mol Biol       Date:  1981       Impact factor: 3.667

5.  A quantitative analysis of the Na+-dependence of Vmax of the fast action potential in mammalian ventricular myocardium. Saturation characteristics and the modulation of a drug-induced INa blockade by [Na+]o.

Authors:  M Kohlhardt
Journal:  Pflugers Arch       Date:  1982-02       Impact factor: 3.657

6.  Low intracellular pH and chemical agents slow inactivation gating in sodium channels of muscle.

Authors:  W Nonner; B C Spalding; B Hille
Journal:  Nature       Date:  1980-03-27       Impact factor: 49.962

7.  [Blocking of gating currents in node of Ranvier membranes after exposure to the quaternary derivative of lidocaine QX-572].

Authors:  G G Gusel'nikova; E M Peganov; B I Khodorov
Journal:  Dokl Akad Nauk SSSR       Date:  1979

8.  Influence of intercellular clefts on potential and current distribution in a multifiber preparation.

Authors:  H G Haas; G Brommundt
Journal:  Biophys J       Date:  1980-05       Impact factor: 4.033

9.  Sodium inactivation mechanism modulates QX-314 block of sodium channels in squid axons.

Authors:  J Z Yeh
Journal:  Biophys J       Date:  1978-11       Impact factor: 4.033

10.  Local anesthetic block of sodium channels in normal and pronase-treated squid giant axons.

Authors:  M D Cahalan
Journal:  Biophys J       Date:  1978-08       Impact factor: 4.033
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  25 in total

1.  Electrophysiological effects of diprafenone, a dimethyl congener of propafenone on guinea-pig ventricular cells.

Authors:  I Kodama; R Suzuki; H Honjo; J Toyama
Journal:  Br J Pharmacol       Date:  1992-11       Impact factor: 8.739

2.  Electrophysiological effects of CRE-1087 in guinea-pig ventricular muscles.

Authors:  E Delpón; C Valenzuela; O Pérez; J Tamargo
Journal:  Br J Pharmacol       Date:  1992-10       Impact factor: 8.739

3.  Block of single cardiac Na+ channels by antiarrhythmic drugs: the effect of amiodarone, propafenone and diprafenone.

Authors:  M Kohlhardt; H Fichtner
Journal:  J Membr Biol       Date:  1988-05       Impact factor: 1.843

4.  On the relationship between V max of slow responses and Ca-current availability in whole-cell clamped guinea pig heart cells.

Authors:  C O Malécot; W Trautwein
Journal:  Pflugers Arch       Date:  1987-09       Impact factor: 3.657

5.  Electrophysiological effects of E-3753, a new antiarrhythmic drug, in guinea-pig ventricular muscle.

Authors:  E Delpón; C Valenzuela; J Tamargo
Journal:  Br J Pharmacol       Date:  1989-04       Impact factor: 8.739

Review 6.  Propafenone. A reappraisal of its pharmacology, pharmacokinetics and therapeutic use in cardiac arrhythmias.

Authors:  H M Bryson; K J Palmer; H D Langtry; A Fitton
Journal:  Drugs       Date:  1993-01       Impact factor: 9.546

7.  Use-dependent effects of pirmenol on Vmax and conduction in guinea-pig ventricular myocardium.

Authors:  J Hasegawa; S Hirai; N Noguchi; I Hisatome; H Kotake; H Mashiba
Journal:  Br J Pharmacol       Date:  1990-04       Impact factor: 8.739

8.  Effects of propafenone on 45Ca movements and contractile responses in vascular smooth muscle.

Authors:  R Carrón; F Pérez-Vizcaino; E Delpón; J Tamargo
Journal:  Br J Pharmacol       Date:  1991-06       Impact factor: 8.739

Review 9.  New antiarrhythmic drugs in pediatric use: propafenone.

Authors:  T Paul; J Janousek
Journal:  Pediatr Cardiol       Date:  1994 Jul-Aug       Impact factor: 1.655

10.  Responsiveness of cardiac Na+ channels to antiarrhythmic drugs: the role of inactivation.

Authors:  I Benz; M Kohlhardt
Journal:  J Membr Biol       Date:  1991-06       Impact factor: 1.843
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