Literature DB >> 6302350

Maternally derived immune resistance to fatal diarrhea in infant mice due to mouse hepatitis virus.

T Ishida, K Fujiwara.   

Abstract

Adult female ICR mice were able to produce high titered neutralizing antibodies to mouse hepatitis virus (MHV) by repeated intraperitoneal injections of formalin-inactivated virus. Offspring sucklings born to the immunized dams resisted to MHV causing fatal diarrhea, when their dams had a complement fixing antibody titer of 1:5 or higher. The protection was found to be mediated mainly through neutralizing IgG antibodies in the milk. Sucklings from non-immune dams were also protected by foster-nursing by immune mothers.

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Year:  1982        PMID： 6302350

Source DB:  PubMed          Journal:  Jpn J Exp Med        ISSN： 0021-5031


  4 in total

1.  Mouse hepatitis virus and host determinants of vertical transmission and maternally-derived passive immunity in mice.

Authors:  S W Barthold; D S Beck; A L Smith
Journal:  Arch Virol       Date:  1988       Impact factor: 2.574

2.  Passively acquired challenge immunity to enterotropic coronavirus in mice.

Authors:  F R Homberger; S W Barthold
Journal:  Arch Virol       Date:  1992       Impact factor: 2.574

3.  Maternally-derived passive immunity to enterotropic mouse hepatitis virus.

Authors:  F R Homberger
Journal:  Arch Virol       Date:  1992       Impact factor: 2.574

4.  Maternal antibodies protect immunoglobulin deficient neonatal mice from mouse hepatitis virus (MHV)-associated wasting syndrome.

Authors:  E Gustafsson; G Blomqvist; A Bellman; R Holmdahl; A Mattsson; R Mattsson
Journal:  Am J Reprod Immunol       Date:  1996-07       Impact factor: 3.886
  4 in total

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