Literature DB >> 6302131

Pseudorabies virus nucleocapsid antigen for skin testing in swine.

G Scherba, J J Turek, D P Gustafson.   

Abstract

A procedure is described for the production of an effective pseudorabies virus skin test antigen consisting of nucleocapsids. The nucleocapsids were prepared by disruption of pseudorabies virus-infected pig kidney cells and nonionic detergent removal of the viral envelope. This preparation was noninfectious for pig kidney cell cultures and mice. Swine that had recovered from a pseudorabies virus infection and were injected intradermally with the nucleocapsid antigen developed a delayed type hypersensitivity response similar to that induced by inactivated virion antigen. The major advantage of the nucleocapsid antigen is that the occasional problem of seroconversion that is encountered with the virion antigen is avoided.

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Year:  1983        PMID： 6302131      PMCID： PMC272681          DOI： 10.1128/jcm.17.3.539-544.1983

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  10 in total

1.  Diagnostic skin test reactions with varicella virus antigen and clinical application of the test.

Authors:  H Kamiya; T Ihara; A Hattori; T Iwasa; M Sakurai; T Izawa; A Yamada; M Takahashi
Journal:  J Infect Dis       Date:  1977-12       Impact factor: 5.226

2.  Comparative analyses of the proteins and antigens of five herpesviruses.

Authors:  R A Killington; J Yeo; R Honess; D H Watson; B E Duncan; I W Halliburton; J Mumford
Journal:  J Gen Virol       Date:  1977-11       Impact factor: 3.891

3.  Comparison of pseudorabies virus inactivated by bromo-ethylene-imine, 60Co irradiation, and acridine dye in immune assay systems.

Authors:  I L Sun; D P Gustafson; G Scherba
Journal:  J Clin Microbiol       Date:  1978-11       Impact factor: 5.948

4.  Skin reactivity and infectious bovine rhinotracheitis.

Authors:  C le Q Darcel; W J Dorward
Journal:  Can Vet J       Date:  1972-04       Impact factor: 1.008

5.  Morphology and entry of enveloped and deenveloped equine abortion (herpes) virus.

Authors:  R A Abodeely; L A Lawson; C C Randall
Journal:  J Virol       Date:  1970-04       Impact factor: 5.103

6.  Delayed hypersensitivity to herpes simplex virus in the guinea pig.

Authors:  R N Lausch; J S Swyers; H E Kaufman
Journal:  J Immunol       Date:  1966-06       Impact factor: 5.422

7.  [Cutaneous hypersensitivity of pigs in Aujesky's disease].

Authors:  R Skoda; S Ivanicová; O Jamrichová; M Sliepka
Journal:  Arch Exp Veterinarmed       Date:  1968

8.  Studies with live varicella vaccine and inactivated skin test antigen: protective effect of the vaccine and clinical application of the skin test.

Authors:  K Baba; H Yabuuchi; H Okuni; M Takahashi
Journal:  Pediatrics       Date:  1978-04       Impact factor: 7.124

9.  A skin test for pseudorabies virus infection in swine.

Authors:  P C Smith; W L Mengeling
Journal:  Can J Comp Med       Date:  1977-10

10.  Size, composition, and structure of the deoxyribonucleic acid of herpes simplex virus subtypes 1 and 2.

Authors:  E D Kieff; S L Bachenheimer; B Roizman
Journal:  J Virol       Date:  1971-08       Impact factor: 5.103
  10 in total

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