Literature DB >> 6301489

Phosphorylation of purified Novikoff hepatoma topoisomerase I.

E Durban, J S Mills, D Roll, H Busch.   

Abstract

The purified Novikoff hepatoma nuclear phosphoprotein with a molecular weight of 110 kdalton and pI 8.4, was found to be a type I topoisomerase. When isolated from 32P-labeled Novikoff ascites cells or incubated in vitro with protein kinase, phosphoserine was found to be its major phosphorylated amino acid. The enzymatic activity of topoisomerase I was altered by changes in phosphorylation. Its activity was increased by protein kinase and it was decreased by alkaline phosphatase.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6301489     DOI： 10.1016/0006-291x(83)91384-0

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  24 in total

1.  Activation of human topoisomerase I by protein kinase CK2.

Authors:  Barbara Kowalska-Loth; Agnieszka Girstun; Rafal Derlacz; Krzysztof Staroń
Journal:  Mol Biol Rep       Date:  2003-06       Impact factor: 2.316

2.  Pea DNA topoisomerase I is phosphorylated and stimulated by casein kinase 2 and protein kinase C.

Authors:  Narendra Tuteja; Malireddy Kodandarami Reddy; Yashwanti Mudgil; Badam Singh Yadav; Meena Rani Chandok; Sudhir Kumar Sopory
Journal:  Plant Physiol       Date:  2003-08       Impact factor: 8.340

3.  Protein kinase CK2 is a central regulator of topoisomerase I hyperphosphorylation and camptothecin sensitivity in cancer cell lines.

Authors:  Keya Bandyopadhyay; Ruth A Gjerset
Journal:  Biochemistry       Date:  2011-01-12       Impact factor: 3.162

4.  Analysis of the structural relationships between the DNA-binding phosphoproteins pp42, pp43 and pp44 by in situ peptide mapping.

Authors:  E Egyhazi; J Stigare; M Holst; A Pigon
Journal:  Mol Biol Rep       Date:  1991-05       Impact factor: 2.316

5.  Non-histone chromatin proteins in beef thyroid: distinct phosphorylation patterns of several protein kinases.

Authors:  S Levasseur; T Poleck; Y Friedman; G Burke
Journal:  Mol Cell Biochem       Date:  1990-06-25       Impact factor: 3.396

6.  Contribution of topoisomerase I to conversion of single-strand into double-strand DNA breaks.

Authors:  B Kowalska-Loth; I Bubko; B Komorowska; I Szumiel; K Staron
Journal:  Mol Biol Rep       Date:  1998-01       Impact factor: 2.316

7.  Inhibition of HeLa cell DNA topoisomerase I by ATP and phosphate.

Authors:  R L Low; J A Holden
Journal:  Nucleic Acids Res       Date:  1985-10-11       Impact factor: 16.971

8.  Phosphorylation of a high molecular weight DNA polymerase alpha.

Authors:  R W Donaldson; E W Gerner
Journal:  Proc Natl Acad Sci U S A       Date:  1987-02       Impact factor: 11.205

9.  Microinjection of anti-topoisomerase I immunoglobulin G into nuclei of Chironomus tentans salivary gland cells leads to blockage of transcription elongation.

Authors:  E Egyházi; E Durban
Journal:  Mol Cell Biol       Date:  1987-12       Impact factor: 4.272

Review 10.  Purification of p53/55 kinase from nuclear ribonucleoproteins of Namalwa cells.

Authors:  D A Graham; J K Deb; H Busch
Journal:  Mol Cell Biochem       Date:  1984-08       Impact factor: 3.396
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.