Literature DB >> 6301467

Ontogenic appearance of Na+ channels characterized as high affinity binding sites for tetrodotoxin during development of the rat nervous and skeletal muscle systems.

A Lombet, T Kazazoglou, E Delpont, J F Renaud, M Lazdunski.   

Abstract

The appearance of the voltage-dependent Na+ channel during the fetal and post-natal development of rat brain, cerebellum and skeletal muscle has been followed using a highly radiolabelled derivative of tetrodotoxin. The number of Na+ channels is low at the fetal stage and increases drastically during post-natal development. The time-course of this increase is different in brain, cerebellum and skeletal muscle. Changes in affinity of the Na+ channel for tetrodotoxin occur during brain and cerebellum development. The results are discussed in relation with the maturation of the three types of excitable tissues.

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Year:  1983        PMID： 6301467     DOI： 10.1016/0006-291x(83)91046-x

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  13 in total

1.  Acetylcholine receptors and sodium channels in denervated and botulinum-toxin-treated adult rat muscle.

Authors:  L Bambrick; T Gordon
Journal:  J Physiol       Date:  1987-01       Impact factor: 5.182

2.  Tissue-specific expression of the RI and RII sodium channel subtypes.

Authors:  D Gordon; D Merrick; V Auld; R Dunn; A L Goldin; N Davidson; W A Catterall
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

3.  The all-or-none role of innervation in expression of apamin receptor and of apamin-sensitive Ca2+-activated K+ channel in mammalian skeletal muscle.

Authors:  H Schmid-Antomarchi; J F Renaud; G Romey; M Hugues; A Schmid; M Lazdunski
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

4.  Photoaffinity-labelling of the calcium-channel-associated 1,4-dihydropyridine and phenylalkylamine receptor in guinea-pig hippocampus. A 195 kDa polypeptide carries both drug receptors and has similarities to the alpha 1 subunit of the purified skeletal-muscle calcium channel.

Authors:  J Striessnig; H G Knaus; H Glossmann
Journal:  Biochem J       Date:  1988-07-01       Impact factor: 3.857

5.  Properties of receptors for neurotoxic phospholipases A2 in different tissues.

Authors:  G Lambeau; M Lazdunski; J Barhanin
Journal:  Neurochem Res       Date:  1991-06       Impact factor: 3.996

6.  A large intracellular pool of inactive Na channel alpha subunits in developing rat brain.

Authors:  J Schmidt; S Rossie; W A Catterall
Journal:  Proc Natl Acad Sci U S A       Date:  1985-07       Impact factor: 11.205

7.  Different functional states of tetrodotoxin sensitive and tetrodotoxin resistant Na+ channels occur during the in vitro development of rat skeletal muscle.

Authors:  C Frelin; H P Vijverberg; G Romey; P Vigne; M Lazdunski
Journal:  Pflugers Arch       Date:  1984-10       Impact factor: 3.657

8.  Comparison of Ca2+-dependent K+ channels in the membrane of smooth muscle cells isolated from adult and foetal human aorta.

Authors:  P D Bregestovski; V Serebryakov; J Stinnakre; A Turmin; V Zamoyski
Journal:  Pflugers Arch       Date:  1988-11       Impact factor: 3.657

9.  Neural regulation of [3H]saxitoxin binding site numbers in rat neonatal muscle.

Authors:  L L Bambrick; T Gordon
Journal:  J Physiol       Date:  1988-12       Impact factor: 5.182

10.  Development of the fast sodium current in early embryonic chick heart cells.

Authors:  S Fujii; R K Ayer; R L DeHaan
Journal:  J Membr Biol       Date:  1988-03       Impact factor: 1.843
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