| Literature DB >> 6301409 |
R J Coelen, D G Jose, J T May.
Abstract
Polybrene was shown to enhance the adsorption of simian sarcoma virus-simian sarcoma associated virus complex (SSV-1/SSAV-1) and baboon endogenous virus (BaEV) onto cells in culture. A 16- to 18-fold increased adsorption of both viruses occurred at 8 micrograms/ml polybrene within one hour after infection. The polybrene mediated adsorption was found to be inhibited by the addition of tri-sodium citrate to the culture medium, suggesting the involvement of electrostatic forces. This contention was further supported by the demonstration of temperature independence of the polybrene mediated interaction.Entities:
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Year: 1983 PMID: 6301409 DOI: 10.1007/bf01314897
Source DB: PubMed Journal: Arch Virol ISSN: 0304-8608 Impact factor: 2.574