Literature DB >> 6300772

The nucleotide sequence of the yeast PHO5 gene: a putative precursor of repressible acid phosphatase contains a signal peptide.

K Arima, T Oshima, I Kubota, N Nakamura, T Mizunaga, A Toh-e.   

Abstract

The nucleotide sequence of the PHO5 gene of the yeast, Saccharomyces cerevisiae, which encodes repressible acid phosphatase (APase) was determined. Comparison of N-terminal amino acid sequence deduced from the nucleotide sequence with that of the purified repressible APase revealed the existence of a putative signal peptide in the precursor protein. The signal peptide was shown to contain 17 amino acid residues and its structural features were quite similar to those of higher eukaryotic and prokaryotic signal peptides. The nucleotide sequence of 5' and 3' noncoding flanking regions of the PHO5 gene are also discussed.

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Year:  1983        PMID： 6300772      PMCID： PMC325827          DOI： 10.1093/nar/11.6.1657

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  39 in total

1.  Isolation and characterization of recessive, constitutive mutations for repressible acid phosphatase synthesis in Saccharomyces cerevisiae.

Authors:  Y Ueda; A To-E; Y Oshima
Journal:  J Bacteriol       Date:  1975-06       Impact factor: 3.490

2.  Biosynthesis of acid phosphatase of baker's yeast. Characterization of a protoplast-bound fraction containing precursors of the exo-enzyme.

Authors:  P Boer; H J Van Rijn; A Reinking; E P Seryn-Parvé
Journal:  Biochim Biophys Acta       Date:  1975-02-19

3.  Functional expression of cloned yeast DNA in Escherichia coli: specific complementation of argininosuccinate lyase (argH) mutations.

Authors:  L Clarke; J Carbon
Journal:  J Mol Biol       Date:  1978-04-25       Impact factor: 5.469

4.  Three forms of the 5.8-S ribosomal RNA species in Saccharomyces cerevisiae.

Authors:  G M Rubin
Journal:  Eur J Biochem       Date:  1974-01-03

5.  Isolation and characterization of acid phosphatase mutants in Saccharomyces cerevisiae.

Authors:  A To-E; Y Ueda; S I Kakimoto; Y Oshima
Journal:  J Bacteriol       Date:  1973-02       Impact factor: 3.490

6.  Human erythrocyte membrane glycoprotein: a re-evaluation of the molecular weight as determined by SDS polyacrylamide gel electrophoresis.

Authors:  J P Segrest; R L Jackson; E P Andrews; V T Marchesi
Journal:  Biochem Biophys Res Commun       Date:  1971-07-16       Impact factor: 3.575

7.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

8.  Genes coding for the structure of the acid phosphatases in Saccharomyces cerevisiae.

Authors:  A Toh-e; S Kakimoto
Journal:  Mol Gen Genet       Date:  1975-12-30

9.  Gene duplication in Saccharomyces cerevisiae.

Authors:  P E Hansche; V Beres; P Lange
Journal:  Genetics       Date:  1978-04       Impact factor: 4.562

10.  Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

Authors:  G Blobel; B Dobberstein
Journal:  J Cell Biol       Date:  1975-12       Impact factor: 10.539
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  34 in total

1.  Studies in the development of Japanese encephalitis vaccine: expression of virus envelope glycoprotein V3 (E) gene in yeast.

Authors:  H Fujita; H Sumiyoshi; C Mori; S Manabe; M Takagi; I Yoshida; K Morita; I Fuke; K Fukai; A Igarashi
Journal:  Bull World Health Organ       Date:  1987       Impact factor: 9.408

2.  Cloning and characterization of a cDNA encoding a maize seedling phytase.

Authors:  S Maugenest; I Martinez; A M Lescure
Journal:  Biochem J       Date:  1997-03-01       Impact factor: 3.857

3.  Evolution of a bifunctional enzyme: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Authors:  J F Bazan; R J Fletterick; S J Pilkis
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

4.  Connections between transcriptional activators, silencers, and telomeres as revealed by functional analysis of a yeast DNA-binding protein.

Authors:  A R Buchman; N F Lue; R D Kornberg
Journal:  Mol Cell Biol       Date:  1988-12       Impact factor: 4.272

5.  Function of the PHO regulatory genes for repressible acid phosphatase synthesis in Saccharomyces cerevisiae.

Authors:  K Yoshida; N Ogawa; Y Oshima
Journal:  Mol Gen Genet       Date:  1989-05

6.  Codon usage in yeast: cluster analysis clearly differentiates highly and lowly expressed genes.

Authors:  P M Sharp; T M Tuohy; K R Mosurski
Journal:  Nucleic Acids Res       Date:  1986-07-11       Impact factor: 16.971

7.  A deletion that includes the segment coding for the signal peptidase cleavage site delays release of Saccharomyces cerevisiae acid phosphatase from the endoplasmic reticulum.

Authors:  R Haguenauer-Tsapis; M Nagy; A Ryter
Journal:  Mol Cell Biol       Date:  1986-02       Impact factor: 4.272

8.  'DNA Strider': a 'C' program for the fast analysis of DNA and protein sequences on the Apple Macintosh family of computers.

Authors:  C Marck
Journal:  Nucleic Acids Res       Date:  1988-03-11       Impact factor: 16.971

9.  Structure and distribution of specific cis-elements for transcriptional regulation of PHO84 in Saccharomyces cerevisiae.

Authors:  N Ogawa; H Saitoh; K Miura; J P Magbanua; M Bun-ya; S Harashima; Y Oshima
Journal:  Mol Gen Genet       Date:  1995-12-10

10.  Primary structure of the nuclear PUT2 gene involved in the mitochondrial pathway for proline utilization in Saccharomyces cerevisiae.

Authors:  K A Krzywicki; M C Brandriss
Journal:  Mol Cell Biol       Date:  1984-12       Impact factor: 4.272
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