Literature DB >> 6300457

Cloning and analysis of reverse transcript P160 genomes of Abelson murine leukemia virus.

S A Latt, S P Goff, C J Tabin, M Paskind, J Y Wang, D Baltimore.   

Abstract

Circular duplex reverse transcripts of the genome of a strain of Abelson murine leukemia virus that encodes a 160,000-molecular-weight protein were isolated, cleaved with HindIII restriction endonuclease, and cloned into the unique HindIII site of lambda phage Charon 21A. Recombinant phage clones, some of which were infectious in transfection assays, were found to contain a 789-base-pair region specific for Abelson murine leukemia virus; this region is not found in other strains of this virus. The extra sequence was localized by restriction endonuclease and electron microscopic heteroduplex analysis. Sequence analysis showed no homology at the ends of the extra sequence, implying that it was deleted by an event that did not utilize sequence homology. The sequence of this unique region has an open reading frame through its entirety.

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Year:  1983        PMID: 6300457      PMCID: PMC256533     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  18 in total

Review 1.  RNA processing and the intervening sequence problem.

Authors:  J Abelson
Journal:  Annu Rev Biochem       Date:  1979       Impact factor: 23.643

2.  Structure of the Abelson murine leukemia virus genome.

Authors:  A Shields; S Goff; M Paskind; G Otto; D Baltimore
Journal:  Cell       Date:  1979-12       Impact factor: 41.582

3.  Direct transformation of 3T3 cells by Abelson murine leukaemia virus.

Authors:  C D Scher; R Siegler
Journal:  Nature       Date:  1975-02-27       Impact factor: 49.962

4.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

5.  A new method for sequencing DNA.

Authors:  A M Maxam; W Gilbert
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

6.  Screening lambdagt recombinant clones by hybridization to single plaques in situ.

Authors:  W D Benton; R W Davis
Journal:  Science       Date:  1977-04-08       Impact factor: 47.728

7.  Lymphosarcoma: virus-induced thymic-independent disease in mice.

Authors:  H T Abelson; L S Rabstein
Journal:  Cancer Res       Date:  1970-08       Impact factor: 12.701

8.  A new technique for the assay of infectivity of human adenovirus 5 DNA.

Authors:  F L Graham; A J van der Eb
Journal:  Virology       Date:  1973-04       Impact factor: 3.616

9.  Construction and characterization of new cloning vehicles. II. A multipurpose cloning system.

Authors:  F Bolivar; R L Rodriguez; P J Greene; M C Betlach; H L Heyneker; H W Boyer; J H Crosa; S Falkow
Journal:  Gene       Date:  1977       Impact factor: 3.688

10.  A defined subgenomic fragment of in vitro synthesized Moloney sarcoma virus DNA can induce cell transformation upon transfection.

Authors:  P Andersson; M P Goldfarb; R A Weinberg
Journal:  Cell       Date:  1979-01       Impact factor: 41.582

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  15 in total

1.  Gag influences transformation by Abelson murine leukemia virus and suppresses nuclear localization of the v-Abl protein.

Authors:  Chae-Ryun Yi; Naomi Rosenberg
Journal:  J Virol       Date:  2007-06-27       Impact factor: 5.103

2.  Isolation of antibodies for phosphotyrosine by immunization with a v-abl oncogene-encoded protein.

Authors:  J Y Wang
Journal:  Mol Cell Biol       Date:  1985-12       Impact factor: 4.272

3.  Isolation of temperature-sensitive Abelson virus mutants by site-directed mutagenesis.

Authors:  A Engelman; N Rosenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

4.  A membrane-associated, carbohydrate-modified form of the v-abl protein that cannot be phosphorylated in vivo or in vitro.

Authors:  S M Watanabe; N E Rosenberg; O N Witte
Journal:  J Virol       Date:  1984-09       Impact factor: 5.103

5.  Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein.

Authors:  G Q Daley; D Baltimore
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

6.  Expression of abl and other oncogenes is independent of metastatic potential in Abelson virus-transformed malignant murine large cell lymphoma.

Authors:  V Rotter; D Wolf; M Blick; G L Nicolson
Journal:  Clin Exp Metastasis       Date:  1985 Apr-Jun       Impact factor: 5.150

7.  The minimum transforming region of v-abl is the segment encoding protein-tyrosine kinase.

Authors:  R Prywes; J G Foulkes; D Baltimore
Journal:  J Virol       Date:  1985-04       Impact factor: 5.103

8.  Temperature-sensitive mutants of Abelson murine leukemia virus deficient in protein tyrosine kinase activity.

Authors:  A Engelman; N Rosenberg
Journal:  J Virol       Date:  1990-09       Impact factor: 5.103

9.  Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-abl.

Authors:  J L Cleveland; M Dean; N Rosenberg; J Y Wang; U R Rapp
Journal:  Mol Cell Biol       Date:  1989-12       Impact factor: 4.272

10.  Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity.

Authors:  J B Konopka; R L Davis; S M Watanabe; A S Ponticelli; L Schiff-Maker; N Rosenberg; O N Witte
Journal:  J Virol       Date:  1984-07       Impact factor: 5.103

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