Literature DB >> 6300170

Diurnal rhythm of beta endorphin in normotensive and hypertensive patients: the effect of clonidine.

C Farsang, L Vajda, J Kapocsi, Z Malisák, S Alföldi, K Varga, I Juhász, G Kunos.   

Abstract

Diurnal rhythm of plasma beta endorphin was established with the highest level in the morning and the lowest one at midnight in normotensive subjects and also in patients with essential hypertension. Clonidine (300 micrograms daily) significantly increased plasma beta endorphin concentrations only in the hypertensive patients. The significant linear correlation between the increase in plasma beta endorphin concentration and the decrease in blood pressure (both systolic and diastolic) in these patients may point to the role of this endogenous opioid in the antihypertensive action of clonidine.

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Year:  1983        PMID： 6300170     DOI： 10.1210/jcem-56-4-865

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN： 0021-972X            Impact factor:   5.958


  7 in total

1.  Plasma beta endorphin in cirrhosis and renal failure.

Authors:  J R Thornton; M S Losowsky
Journal:  Gut       Date:  1991-03       Impact factor: 23.059

2.  Effects of opioid blockade with naltrexone and distraction on cold and ischemic pain in hypertension.

Authors:  Christopher Ring; Christopher R France; Mustafa al'Absi; Louise Beesley; Louisa Edwards; David McIntyre; Douglas Carroll; Una Martin
Journal:  J Behav Med       Date:  2007-01-05

Review 3.  Effects of catecholamines on secretion of adrenocorticotrophic hormone (ACTH) in man.

Authors:  S Al-Damluji; L H Rees
Journal:  J Clin Pathol       Date:  1987-09       Impact factor: 3.411

4.  Effect of clonidine on beta-endorphin, ACTH and cortisol secretion in essential hypertension and obesity.

Authors:  J Słowinska-Srzednicka; S Zgliczynski; P Soszynski; J Puciłowska; M Wierzbicki; W Jeske
Journal:  Eur J Clin Pharmacol       Date:  1988       Impact factor: 2.953

5.  Effects of naltrexone on electrocutaneous pain in patients with hypertension compared to normotensive individuals.

Authors:  Christopher Ring; Christopher R France; Mustafa al'Absi; Louisa Edwards; David McIntyre; Douglas Carroll; Una Martin
Journal:  Biol Psychol       Date:  2007-10-13       Impact factor: 3.251

6.  Diurnal rhythm of plasma beta endorphin, cortisol and growth hormone in schizophrenics as compared to control subjects.

Authors:  I Gil-Ad; Z Dickerman; S Amdursky; Z Laron
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

7.  Effects of opioid blockade on nociceptive flexion reflex thresholds and nociceptive responding in hypertensive and normotensive individuals.

Authors:  Louisa Edwards; Christopher Ring; Christopher R France; David McIntyre; Una Martin
Journal:  Int J Psychophysiol       Date:  2008-03-15       Impact factor: 2.997
  7 in total

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