Literature DB >> 6300022

Structure and function of the hepatitis B virus genome.

H Will, C Kuhn, R Cattaneo, H Schaller.   

Abstract

A preliminary map of the hepatitis B virus genome has been derived from the nucleotide sequence of cloned human hepatitis virus (HBV) DNA. The genes for two viral antigens were identified and their expression was studied using SV40 vector systems. HBV DNA cloned and amplified in bacteria induces hepatitis in chimpanzees demonstrating that the cloned HBV DNA is functionally intact.

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Year:  1982        PMID： 6300022

Source DB:  PubMed          Journal:  Princess Takamatsu Symp


  6 in total

1.  Tight clustering of human hepatitis B virus integration sites in hepatomas near a triple-stranded region.

Authors:  C Shih; K Burke; M J Chou; J B Zeldis; C S Yang; C S Lee; K J Isselbacher; J R Wands; H M Goodman
Journal:  J Virol       Date:  1987-11       Impact factor: 5.103

2.  Defective replication units of hepatitis B virus.

Authors:  P Schranz; H Zentgraf; I F Loncarević; M Niepmann; C H Schröder
Journal:  J Virol       Date:  1990-04       Impact factor: 5.103

3.  X-region-specific transcript in mammalian hepatitis B virus-infected liver.

Authors:  S Kaneko; R H Miller
Journal:  J Virol       Date:  1988-11       Impact factor: 5.103

4.  Expression of hepatitis B antigens with a simian virus 40 vector.

Authors:  H Will; R Cattaneo; E Pfaff; C Kuhn; M Roggendorf; H Schaller
Journal:  J Virol       Date:  1984-05       Impact factor: 5.103

5.  Hepatitis B virus core antigen has two nuclear localization sequences in the arginine-rich carboxyl terminus.

Authors:  S G Eckhardt; D R Milich; A McLachlan
Journal:  J Virol       Date:  1991-02       Impact factor: 5.103

6.  Hepatitis B viruses with precore region defects prevail in persistently infected hosts along with seroconversion to the antibody against e antigen.

Authors:  H Okamoto; S Yotsumoto; Y Akahane; T Yamanaka; Y Miyazaki; Y Sugai; F Tsuda; T Tanaka; Y Miyakawa; M Mayumi
Journal:  J Virol       Date:  1990-03       Impact factor: 5.103
  6 in total

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