| Literature DB >> 6299520 |
R C Brown, A Poole, G T Fleming.
Abstract
The cell transforming ability of asbestos dust was investigated using C3H10T 1/2 murine fibroblasts. In a series of experiments both crocidolite and amosite caused no increase in the number of transformed foci over that seen in cultures from untreated cells. The dusts, were, however, capable of augmenting the oncogenic effect of benzo[a]pyrene (BP). This putative synergistic effect was evident when fibres and chemicals were added to cultures as simple mixtures and when BP was adsorbed to the surface of the fibres.Entities:
Mesh：
Substances：
Year: 1983 PMID： 6299520 DOI： 10.1016/0304-3835(83)90071-x
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679