Literature DB >> 6299449

Single 1 g dose of cefotaxime in the treatment of infections due to penicillinase-producing strains of Neisseria gonorrhoeae.

G A de Koning, D Tio, J A van den Hoek, B van Klingeren.   

Abstract

One hundred and two patients with an uncomplicated infection due to penicillinase-producing strains of Neisseria gonorrhoeae (PPNG) were treated with a single 1 g dose of cefotaxime. At follow-up within 15 days all genital and rectal infections were cured. Pharyngeal infections also seemed to respond to this treatment. A relatively high proportion (30.9%) of patients, however, developed post-gonococcal urethritis.

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Year:  1983        PMID: 6299449      PMCID: PMC1046147          DOI: 10.1136/sti.59.2.100

Source DB:  PubMed          Journal:  Br J Vener Dis        ISSN: 0007-134X


  8 in total

1.  Cefotaxime for spectinomycin resistant Neisseria gonorrhoeae.

Authors:  A J Boakes; J Barrow; S J Eykyn; I Phillips
Journal:  Lancet       Date:  1981-07-11       Impact factor: 79.321

2.  Pharmacokinetics of cefotaxime.

Authors:  K P Fu; P Aswapokee; I Ho; C Matthijssen; H C Neu
Journal:  Antimicrob Agents Chemother       Date:  1979-11       Impact factor: 5.191

3.  In vitro activity of cefotaxime and other cephalosporins against Neisseria gonorrhoeae.

Authors:  P Piot; E Van Dyck; J Colaert; J P Ursi
Journal:  J Antimicrob Chemother       Date:  1980-09       Impact factor: 5.790

4.  Gonorrhea in Rotterdam caused by penicillinase-producing gonococci.

Authors:  K C Nayyar; R C Noble; M F Michel; E Stolz
Journal:  Br J Vener Dis       Date:  1980-08

5.  [The spread of penicillinase-forming gonococci in Amsterdam].

Authors:  R A Coutinho; F Jansen Schoonhoven; M C Ansink-Schipper; G A de Koning; D Tio
Journal:  Ned Tijdschr Geneeskd       Date:  1982-01-30

6.  In vitro antimicrobial activity of cefoperazone, cefotaxime, moxalactam (LY127935), azlocillin, mezlocillin, and other beta-lactam antibiotics against Neisseria gonorrhoeae and Haemophilus influenzae, including beta-lactamase-producing strains.

Authors:  C N Baker; C Thornsberry; R N Jones
Journal:  Antimicrob Agents Chemother       Date:  1980-04       Impact factor: 5.191

7.  Treatment of uncomplicated gonorrhea with cefotaxime.

Authors:  H H Handsfield; K K Holmes
Journal:  Sex Transm Dis       Date:  1981 Jul-Sep       Impact factor: 2.830

8.  Biochemical and genetical approaches to the mechanism of action of penicillin.

Authors:  B G Spratt
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1980-05-16       Impact factor: 6.237

  8 in total
  4 in total

Review 1.  Role of cephalosporins in gonorrhoea and other sexually transmitted diseases.

Authors:  I Phillips
Journal:  Drugs       Date:  1987       Impact factor: 9.546

Review 2.  Cefotaxime. An update of its pharmacology and therapeutic use.

Authors:  P A Todd; R N Brogden
Journal:  Drugs       Date:  1990-10       Impact factor: 9.546

Review 3.  Beta-lactams in sexually transmitted diseases: rationale for selection and dosing regimens.

Authors:  D Kunimoto; R Brunham; A Ronald
Journal:  Eur J Clin Microbiol       Date:  1984-12       Impact factor: 3.267

4.  Tolerability, Safety, Pharmacokinetics and Drug Interaction of Cefotaxime Sodium-Tazobactam Sodium Injection (6:1) Following Single and Multiple Intravenous Doses in Chinese Healthy Subjects.

Authors:  Ning Chen; Lu-Ning Sun; Wen-Hui Hu; Yi-Ya Wang; Li-Jun Xie; Juan Cheng; Hong-Wen Zhang; Yun Liu; Yong-Qing Wang; Li Ding
Journal:  Front Pharmacol       Date:  2020-07-08       Impact factor: 5.810

  4 in total

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