Literature DB >> 6299368

Iodination of arachidonic acid mediated by eosinophil peroxidase, myeloperoxidase and lactoperoxidase. Identification and comparison of products.

J Turk, W R Henderson, S J Klebanoff, W C Hubbard.   

Abstract

Arachidonic acid undergoes iodination in the presence of hydrogen peroxide, iodide, and either eosinophil peroxidase, myeloperoxidase or lactoperoxidase. The profile of products generated by each of the three peroxidases is similar as determined by reversed-phase high-performance liquid chromatography. Structural analysis of the products indicate that: 1, each of the four double bonds in arachidonic acid is susceptible to iodination; 2, arachidonic acid can be multiply iodinated; and 3, the carboxylate moiety does not participate in the formation of all products. The isomeric composition of the isolated products indicates that peroxidase-mediated iodination of arachidonate is not stereoselective.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6299368     DOI： 10.1016/0005-2760(83)90173-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  5 in total

1.  Enhanced killing of Acanthamoeba cysts with a plant peroxidase-hydrogen peroxide-halide antimicrobial system.

Authors:  Reanne Hughes; Peter W Andrew; Simon Kilvington
Journal:  Appl Environ Microbiol       Date:  2003-05       Impact factor: 4.792

2.  Activation and release of enzymes and major basic protein from guinea pig eosinophil granulocytes induced by different inflammatory stimuli and other substances. A histochemical, biochemical, and electron microscopic study.

Authors:  H Popper; G Knipping; B M Czarnetzki; R Steiner; G Helleis; H Auer
Journal:  Inflammation       Date:  1989-04       Impact factor: 4.092

Review 3.  Non-union bone fractures.

Authors:  Britt Wildemann; Anita Ignatius; Frankie Leung; Lisa A Taitsman; R Malcolm Smith; Rodrigo Pesántez; Martin J Stoddart; R Geoff Richards; Jesse B Jupiter
Journal:  Nat Rev Dis Primers       Date:  2021-08-05       Impact factor: 52.329

4.  Broad-Spectrum Antimicrobial Effects of Photocatalysis Using Titanium Dioxide Nanoparticles Are Strongly Potentiated by Addition of Potassium Iodide.

Authors:  Ying-Ying Huang; Hwanjun Choi; Yu Kushida; Brijesh Bhayana; Yuguang Wang; Michael R Hamblin
Journal:  Antimicrob Agents Chemother       Date:  2016-08-22       Impact factor: 5.191

5.  Mechanistic aspects of ingested chlorine dioxide on thyroid function: impact of oxidants on iodide metabolism.

Authors:  J P Bercz; L L Jones; R M Harrington; R Bawa; L Condie
Journal:  Environ Health Perspect       Date:  1986-11       Impact factor: 9.031
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.