Literature DB >> 6299182

Effect of ketoconazole on the fungicidal action of amphotericin B in Candida albicans.

I J Sud, D S Feingold.   

Abstract

Amphotericin B-susceptible Candida albicans became resistant to the drug after growth in the presence of ketoconazole. Chromatographic analysis of cellular sterols showed that the organisms became depleted of ergosterol in parallel with the development of amphotericin B resistance. The implications of these findings are discussed in relation to combination chemotherapy with these two important antifungal agents.

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Year:  1983        PMID： 6299182      PMCID： PMC184642          DOI： 10.1128/AAC.23.1.185

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  19 in total

1.  In vitro studies with combinations of 5-fluorocytosine and amphotericin B.

Authors:  S Shadomy; G Wagner; E Espinel-Ingroff; B A Davis
Journal:  Antimicrob Agents Chemother       Date:  1975-08       Impact factor: 5.191

2.  Two types of resistance to polyene antibiotics in Candida albicans.

Authors:  C C HsuChen; D S Feingold
Journal:  Nature       Date:  1974-10-18       Impact factor: 49.962

3.  Combined amphotericin B-tetracycline therapy for experimental coccidioidomycosis.

Authors:  M Huppert; S H Sun; K R Vukovich
Journal:  Antimicrob Agents Chemother       Date:  1974-05       Impact factor: 5.191

4.  Synergistic action of amphotericin B and 5-fluorocytosine against yeast-like organisms.

Authors:  G Medoff; M Comfort; G S Kobayashi
Journal:  Proc Soc Exp Biol Med       Date:  1971-11

5.  Relationship between polyene resistance and sterol compositions in Cryptococcus neoformans.

Authors:  S J Kim; J Kwon-Chung; G W Milne; W B Hill; G Patterson
Journal:  Antimicrob Agents Chemother       Date:  1975-01       Impact factor: 5.191

6.  Synergistic action of amphotericin B and rifampin against Candida species.

Authors:  W H Beggs; G A Sarosi; M I Walker
Journal:  J Infect Dis       Date:  1976-02       Impact factor: 5.226

7.  Selective membrane toxicity of the polyene antibiotics: studies on lecithin membrane models (liposomes).

Authors:  C C Hsuchen; D S Feingold
Journal:  Antimicrob Agents Chemother       Date:  1973-09       Impact factor: 5.191

8.  In vitro inhibition of Coccidioides immitis strains with amphotericin B plus rifampin.

Authors:  D Rifkind; E D Crowder; R N Hyland
Journal:  Antimicrob Agents Chemother       Date:  1974-12       Impact factor: 5.191

9.  Activity of amphotericin B, 5-fluorocytosine, and rifampin against six clinical isolates of Aspergillus.

Authors:  M Kitahara; V K Seth; G Medoff; G S Kobayashi
Journal:  Antimicrob Agents Chemother       Date:  1976-06       Impact factor: 5.191

10.  Selective membrane toxicity of the polyene antibiotics: studies on natural membranes.

Authors:  C C Hsuchen; D S Feingold
Journal:  Antimicrob Agents Chemother       Date:  1973-09       Impact factor: 5.191
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  14 in total

Review 1.  Combination antifungal therapy.

Authors:  Melissa D Johnson; Conan MacDougall; Luis Ostrosky-Zeichner; John R Perfect; John H Rex
Journal:  Antimicrob Agents Chemother       Date:  2004-03       Impact factor: 5.191

2.  Self-induced nystatin resistance in Dictyostelium discoideum.

Authors:  D P Kasbekar; S Madigan; E R Katz
Journal:  Antimicrob Agents Chemother       Date:  1985-06       Impact factor: 5.191

3.  Activity of amphotericin B and intraconazole against intraphagocytic Candida albicans.

Authors:  E Ponce; J C Pechère
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1990-10       Impact factor: 3.267

4.  High-frequency, in vitro reversible switching of Candida lusitaniae clinical isolates from amphotericin B susceptibility to resistance.

Authors:  S A Yoon; J A Vazquez; P E Steffan; J D Sobel; R A Akins
Journal:  Antimicrob Agents Chemother       Date:  1999-04       Impact factor: 5.191

Review 5.  Treatment of systemic fungal infections: recent progress and current problems.

Authors:  T J Walsh; A Pizzo
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1988-08       Impact factor: 3.267

6.  Candida septic thrombosis of the great central veins associated with central catheters. Clinical features and management.

Authors:  W D Strinden; R B Helgerson; D G Maki
Journal:  Ann Surg       Date:  1985-11       Impact factor: 12.969

7.  Susceptibilities of serial Cryptococcus neoformans isolates from patients with recurrent cryptococcal meningitis to amphotericin B and fluconazole.

Authors:  A Casadevall; E D Spitzer; D Webb; M G Rinaldi
Journal:  Antimicrob Agents Chemother       Date:  1993-06       Impact factor: 5.191

8.  Antagonistic effects of fluconazole and 5-fluorocytosine on candidacidal action of amphotericin B in human serum.

Authors:  E Martin; F Maier; S Bhakdi
Journal:  Antimicrob Agents Chemother       Date:  1994-06       Impact factor: 5.191

9.  Novel synergism of two antifungal agents, copiamycin and imidazole.

Authors:  J Uno; M L Shigematsu; T Arai
Journal:  Antimicrob Agents Chemother       Date:  1983-10       Impact factor: 5.191

10.  Effect of ketoconazole on lethal action of amphotericin B on Leishmania mexicana promastigotes.

Authors:  H Ramos; M Saint-Pierre-Chazalet; J Bolard; B E Cohen
Journal:  Antimicrob Agents Chemother       Date:  1994-05       Impact factor: 5.191
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