Literature DB >> 6297966

Identification of a Mr 58 000 glycoprotein subunit of the opiate receptor.

W A Klee, W F Simonds, F W Sweat, T R Burke, A E Jacobson, K C Rice.   

Abstract

A Mr 58 000 subunit of the opiate receptor has been identified using tritiated fentanyl isothiocyanate, a potent opiate alkylating reagent with specificity for the delta-opiate receptor subclass. The subunit is alkylated in the presence of dextrorphan but not levorphanol. The specifically labelled protein was retained on columns of immobilized wheat germ agglutinin and is therefore presumably a glycoprotein. Partial purification of the Mr 58 000 opiate receptor subunit from neuroblastoma X glioma NG108-15 hybrid cell membranes is described.

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Year:  1982        PMID： 6297966     DOI： 10.1016/0014-5793(82)81318-5

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  8 in total

Review 1.  The molecular structure of opiate receptors.

Authors:  M Wollemann
Journal:  Neurochem Res       Date:  1987-02       Impact factor: 3.996

2.  Purification and characterization of the mu opiate receptor from rat brain using affinity chromatography.

Authors:  R Maneckjee; R S Zukin; S Archer; J Michael; P Osei-Gyimah
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

3.  Preparation of [125I-Tyr27,Leu5]beta h-endorphin and its use for crosslinking of opioid binding sites in human striatum and NG108-15 neuroblastoma-glioma cells.

Authors:  D M Helmeste; R G Hammonds; C H Li
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

4.  Morphine enhances the phosphorylation of a 58 kDa protein in mouse brain membranes.

Authors:  K Nagamatsu; K Suzuki; R Teshima; H Ikebuchi; T Terao
Journal:  Biochem J       Date:  1989-01-01       Impact factor: 3.857

5.  Procaine isothiocyanate: an irreversible inhibitor of the specific binding of [3H]batrachotoxinin-A benzoate to sodium channels.

Authors:  C R Creveling; M E Bell; T R Burke; E Chang; G A Lewandowski-Lovenberg; C H Kim; K C Rice; J W Daly
Journal:  Neurochem Res       Date:  1990-04       Impact factor: 3.996

6.  Purification of the opiate receptor of NG108-15 neuroblastoma-glioma hybrid cells.

Authors:  W F Simonds; T R Burke; K C Rice; A E Jacobson; W A Klee
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

7.  Electrophilic derivatives of purines as irreversible inhibitors of A1 adenosine receptors.

Authors:  K A Jacobson; S Barone; U Kammula; G L Stiles
Journal:  J Med Chem       Date:  1989-05       Impact factor: 7.446

8.  β-Arrestin-dependent ERK signaling reduces anxiety-like and conditioned fear-related behaviors in mice.

Authors:  Mee Jung Ko; Terrance Chiang; Arbaaz A Mukadam; Grace E Mulia; Anna M Gutridge; Angel Lin; Julia A Chester; Richard M van Rijn
Journal:  Sci Signal       Date:  2021-08-03       Impact factor: 8.192
  8 in total

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