[Role of enkephalin-reactive system of the caudate nucleus in acquisition of alimentary conditioned reflex in dogs].

Bilateral injections of 15 and 45 mcg of synthetic analogue of TYR-D-ALA-LEY-Enkefaline-ARG into the body of the caudate nuclei in dogs produced a manifested increase in parameters of Pavlovian alimentary conditioned reflexes. Moreover, the dose of 15 mcg of LEY-enkefaline enhanced the background salivation and prolonged food consumption. Excited dogs became calm. During analogous injections into the right lateral hypothalamus the effect diminished while injections of 15 mcg of morphine hydrochloride were ineffective. The data point to role of the enkefaline-containing system in alimentary behaviour.