| Literature DB >> 6296179 |
Y C Cheng, R F Schinazi, G E Dutschman, R S Tan, S P Grill.
Abstract
A rapid, reproducible and objective new method for typing herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) based on the effects of virus-induced thymidine kinases on various antiviral drugs has been developed. When several laboratory strains and clinical isolates were typed by this method and compared to the results obtained by the immunofluorescence antibody typing method, agreement was found for all the viruses. The new technique has the added advantage of determining the sensitivity of HSV strains to antiviral drugs.Mesh：
Substances：
Year: 1982 PMID： 6296179 DOI： 10.1016/0166-0934(82)90011-8
Source DB: PubMed Journal: J Virol Methods ISSN： 0166-0934 Impact factor: 2.014