Literature DB >> 6295271

Activity of ketoconazole and its deacyl derivative against Plasmodium falciparum and Candida isolates.

M A Pfaller, J J Segal, D J Krogstad.   

Abstract

Deacylketoconazole was 15- to 50-fold more active against Plasmodium falciparum than was ketoconazole, based on [(3)H]hypoxanthine uptake and quantitative parasite counts. In contrast, there were no significant differences between these drugs in their activity against clinical isolates of Candida spp.

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Year:  1982        PMID： 6295271      PMCID： PMC185686          DOI： 10.1128/AAC.22.5.917

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  13 in total

1.  Plasmodium falciparum: microaerophilic requirements in human red blood cells.

Authors:  L W Scheibel; S H Ashton; W Trager
Journal:  Exp Parasitol       Date:  1979-06       Impact factor: 2.011

2.  Antimalarial activity of S-isobutyl adenosine against Plasmodium falciparum in culture.

Authors:  W Trager; M Robert-Gero; E Lederer
Journal:  FEBS Lett       Date:  1978-01-15       Impact factor: 4.124

3.  Miconazole, a broad-spectrum antimycotic agent with antibacterial activity.

Authors:  J M Van Cutsem; D Thienpont
Journal:  Chemotherapy       Date:  1972       Impact factor: 2.544

4.  Variability of agar dilution-replicator method of yeast susceptibility testing.

Authors:  C Brass; J Z Shainhouse; D A Stevens
Journal:  Antimicrob Agents Chemother       Date:  1979-06       Impact factor: 5.191

5.  Miconazole therapy for treatment of fungal infections in cancer patients.

Authors:  W M Jordan; G P Bodey; V Rodriguez; S J Ketchel; J Henney
Journal:  Antimicrob Agents Chemother       Date:  1979-12       Impact factor: 5.191

6.  Human malaria parasites in continuous culture.

Authors:  W Trager; J B Jensen
Journal:  Science       Date:  1976-08-20       Impact factor: 47.728

7.  Ketoconazole, an oral antifungal: laboratory and clinical assessment of imidazole drugs.

Authors:  D Borelli; J L Bran; J Fuentes; R Legendre; E Leiderman; H B Levine; A Restrepo; D A Stevens
Journal:  Postgrad Med J       Date:  1979-09       Impact factor: 2.401

8.  Sensitivity of Candida albicans from patients with chronic oral candidiasis.

Authors:  W P Holbrook; R Kippax
Journal:  Postgrad Med J       Date:  1979-09       Impact factor: 2.401

9.  Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique.

Authors:  R E Desjardins; C J Canfield; J D Haynes; J D Chulay
Journal:  Antimicrob Agents Chemother       Date:  1979-12       Impact factor: 5.191

10.  Comparison of the in vitro antifungal activities of miconazole and a new imidazole, R41,400.

Authors:  D Dixon; S Shadomy; H J Shadomy; A Espinel-Ingroff; T M Kerkering
Journal:  J Infect Dis       Date:  1978-08       Impact factor: 5.226
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  4 in total

1.  In vitro activity of antifungal drugs against Plasmodium falciparum field isolates.

Authors:  Peter Pongratz; Florian Kurth; Ghyslain Mombo Ngoma; Arti Basra; Michael Ramharter
Journal:  Wien Klin Wochenschr       Date:  2011-07-07       Impact factor: 1.704

2.  Potent antimalarial activity of clotrimazole in in vitro cultures of Plasmodium falciparum.

Authors:  T Tiffert; H Ginsburg; M Krugliak; B C Elford; V L Lew
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-04       Impact factor: 11.205

3.  The use of 5-fluorocytosine and ketoconazole in the culture of the erythrocytic stages of Plasmodium falciparum and some tumor cell lines.

Authors:  E F Roth; J C McKitrick; F Herz
Journal:  Experientia       Date:  1989-05-15

4.  Exploiting large-scale drug-protein interaction information for computational drug repurposing.

Authors:  Ruifeng Liu; Narender Singh; Gregory J Tawa; Anders Wallqvist; Jaques Reifman
Journal:  BMC Bioinformatics       Date:  2014-06-20       Impact factor: 3.169
  4 in total

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