T-lymphocyte colonies in malignant disease.

T-lymphocyte colonies have been cultured in 106 subjects comprising healthy individuals and hospital inpatients as controls and patients with a wide variety of malignancies. Abnormal results were recorded in 89% of patients with malignant disease and in 23 of 24 patients with carcinomas (96%). This test may be valuable in research, and in diagnosis and monitoring of progress in malignant disease.