Literature DB >> 6294215

Incidence and toxicological aspects of drugs detected in 484 fatally injured drivers and pedestrians in Ontario.

G Cimbura, D M Lucas, R C Bennett, R A Warren, H M Simpson.   

Abstract

Results are presented of a comprehensive drug study carried out on specimens from drivers and pedestrians fatally injured in Ontario. Toxicological analyses were regularly performed on blood and urine and occasionally on vitreous humor, stomach contents, and liver. The analytical procedures could detect and quantitate a wide variety of drugs including such illicit drugs as Cannabis. With respect to drivers, alcohol was found in 57% of the study sample and drugs other than alcohol, in 26%. However, in only 9.5% of the drivers were psychoactive drugs (other than alcohol) detected in the blood in concentrations that may adversely affect driving skills. Delta-9-Tetrahydrocannabinol and diazepam accounted for a majority of the findings in this category.

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Year:  1982        PMID: 6294215

Source DB:  PubMed          Journal:  J Forensic Sci        ISSN: 0022-1198            Impact factor:   1.832


  13 in total

1.  On the high road: driving under the influence of cannabis in Ontario.

Authors:  G W Walsh; R E Mann
Journal:  Can J Public Health       Date:  1999 Jul-Aug

Review 2.  Benzodiazepine use and motor vehicle accidents. Systematic review of reported association.

Authors:  R E Thomas
Journal:  Can Fam Physician       Date:  1998-04       Impact factor: 3.275

3.  [Role of drugs in traffic accidents. A pilot study of traffic accident offenders in Switzerland (Bern region)].

Authors:  L Ulrich; O Rudin; A Amsler; P Zink
Journal:  Z Rechtsmed       Date:  1984

Review 4.  The relationship between benzodiazepine use and traffic accidents: A systematic literature review.

Authors:  Beitske E Smink; Antoine C G Egberts; Klaas J Lusthof; Donald R A Uges; Johan J de Gier
Journal:  CNS Drugs       Date:  2010-08       Impact factor: 5.749

Review 5.  Effects of terfenadine on psychomotor performance. An overview.

Authors:  D W Aaronson
Journal:  Drug Saf       Date:  1993-04       Impact factor: 5.606

Review 6.  Benzodiazepine poisoning. Clinical and pharmacological considerations and treatment.

Authors:  P Gaudreault; J Guay; R L Thivierge; I Verdy
Journal:  Drug Saf       Date:  1991 Jul-Aug       Impact factor: 5.606

Review 7.  H1-receptor antagonists. Comparative tolerability and safety.

Authors:  F E Simons
Journal:  Drug Saf       Date:  1994-05       Impact factor: 5.606

8.  Histamine H1 receptor occupancy in human brains after single oral doses of histamine H1 antagonists measured by positron emission tomography.

Authors:  K Yanai; J H Ryu; T Watanabe; R Iwata; T Ido; Y Sawai; K Ito; M Itoh
Journal:  Br J Pharmacol       Date:  1995-09       Impact factor: 8.739

9.  Cost-benefit analysis of first-generation antihistamines in the treatment of allergic rhinitis.

Authors:  Patrick W Sullivan; Sheryl L Follin; Michael B Nichol
Journal:  Pharmacoeconomics       Date:  2004       Impact factor: 4.981

10.  Being "at fault" in traffic crashes: does alcohol, cannabis, cocaine, or polydrug abuse make a difference?

Authors:  M L Chipman; S Macdonald; R E Mann
Journal:  Inj Prev       Date:  2003-12       Impact factor: 2.399

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