Literature DB >> 6294119

Characterization of sarcomeric myosin heavy chain genes.

R M Wydro, H T Nguyen, R M Gubits, B Nadal-Ginard.   

Abstract

Myosin heavy chain is encoded by a large multigene family. Using pMHC-25, a recombinant cDNA clone isolated from the rat myogenic cell line L6E9, four members of this family in the rat have been isolated and shown to be tissue-specific and developmentally regulated. The coding regions of these genes share regions of homology interspaced with regions of non-homology. Detailed analysis of one embryonic and one adult myosin heavy chain gene shows that the coding sequences are interrupted by numerous intervening sequences whose number, size, and distribution do not appear to be conserved in the same organism or between species.

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Year:  1983        PMID： 6294119

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  37 in total

1.  Characterization of diverse forms of myosin heavy chain expressed in adult human skeletal muscle.

Authors:  L Saez; L A Leinwand
Journal:  Nucleic Acids Res       Date:  1986-04-11       Impact factor: 16.971

2.  Functional domains of the Drosophila melanogaster muscle myosin heavy-chain gene are encoded by alternatively spliced exons.

Authors:  E L George; M B Ober; C P Emerson
Journal:  Mol Cell Biol       Date:  1989-07       Impact factor: 4.272

3.  Structural alterations in chromatin during myogenesis in the chicken.

Authors:  I J Wiid; G Durrheim; A J Bester; P D van Helden
Journal:  Mol Cell Biochem       Date:  1988-01       Impact factor: 3.396

4.  Multiple positive and negative 5' regulatory elements control the cell-type-specific expression of the embryonic skeletal myosin heavy-chain gene.

Authors:  P F Bouvagnet; E E Strehler; G E White; M A Strehler-Page; B Nadal-Ginard; V Mahdavi
Journal:  Mol Cell Biol       Date:  1987-12       Impact factor: 4.272

5.  Myoglobin expression: early induction and subsequent modulation of myoglobin and myoglobin mRNA during myogenesis.

Authors:  P A Weller; M Price; H Isenberg; Y H Edwards; A J Jeffreys
Journal:  Mol Cell Biol       Date:  1986-12       Impact factor: 4.272

6.  Characterization of human cardiac myosin heavy chain genes.

Authors:  K Yamauchi-Takihara; M J Sole; J Liew; D Ing; C C Liew
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

7.  Thyroid hormone regulates expression of a transfected alpha-myosin heavy-chain fusion gene in fetal heart cells.

Authors:  T A Gustafson; B E Markham; J J Bahl; E Morkin
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

8.  A long polypyrimidine/polypurine tract induces an altered DNA conformation on the 3' coding region of the adjacent myosin heavy chain gene.

Authors:  J G McCarthy; S M Heywood
Journal:  Nucleic Acids Res       Date:  1987-10-12       Impact factor: 16.971

9.  Characterization of a human genomic DNA fragment coding for a myosin heavy chain.

Authors:  H Appelhans; H P Vosberg
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

10.  Induced formation and maturation of acetylcholine receptor clusters in a defined 3D bio-artificial muscle.

Authors:  Lin Wang; Janet Shansky; Herman Vandenburgh
Journal:  Mol Neurobiol       Date:  2013-01-31       Impact factor: 5.590
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