Literature DB >> 6293073

[Management of advanced breast cancer in post-menopausal women. A comparative trial of hormonal therapy, chemotherapy, and a combination of both].

B Clavel, J P Cappelaere, J Guerin, T Klein, E Pommatau, J Berlie.   

Abstract

A randomized trial was done in 98 post-menopausal women with breast cancer. Hormonal receptors had not been assayed in any patient. Patients were given hormonal therapy with tamoxifen and drostanolone propionate (n = 34), or chemotherapy with the CMF protocol (n = 30), or a combination of both (n = 34). The results are in favour of hormonal therapy alone, which gave the best immediate objective responses, the least adverse side-effects, and possibly improved survival rates.

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Year:  1982        PMID: 6293073

Source DB:  PubMed          Journal:  Sem Hop


  3 in total

Review 1.  Chemotherapy alone versus endocrine therapy alone for metastatic breast cancer.

Authors:  N Wilcken; J Hornbuckle; D Ghersi
Journal:  Cochrane Database Syst Rev       Date:  2003

2.  Seven new metabolites of drostanolone heptanoate by using Beauveria bassiana, and Macrophomina phaseolina cell suspension cultures.

Authors:  Zahid Hussain; Nusrat Hussain; Shabbir Hussain; M Iqbal Choudhary
Journal:  RSC Adv       Date:  2020-01-02       Impact factor: 4.036

3.  Bio-Catalytic Structural Transformation of Anti-cancer Steroid, Drostanolone Enanthate with Cephalosporium aphidicola and Fusarium lini, and Cytotoxic Potential Evaluation of Its Metabolites against Certain Cancer Cell Lines.

Authors:  M Iqbal Choudhary; Mahwish Siddiqui; Sammer Yousuf; Narjis Fatima; Malik S Ahmad; Hani Choudhry
Journal:  Front Pharmacol       Date:  2017-12-20       Impact factor: 5.810

  3 in total

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