Literature DB >> 6292788

Characterization of beta-adrenergic receptors on human cerebral microvessels.

H Kobayashi, L Frattola, C Ferrarese, P Spano, M Trabucchi.   

Abstract

Cerebral microvessels were separated and prepared from human brain cortex by albumin floatation and glass bead filtration. The binding of a specific beta-adrenergic antagonist, (125I) iodohydroxybenzylpindolol, to the microvessel preparation was characterized by high affinity, saturability, and stereospecificity. The presence of specific beta-adrenergic receptor sites in human cerebral microvessels supports the hypothesis of adrenergic regulation of the function of cerebral microvessels.

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Year:  1982        PMID： 6292788     DOI： 10.1212/wnl.32.12.1384

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  7 in total

1.  Adrenergic receptors coupled to adenylate cyclase in human cerebromicrovascular endothelium.

Authors:  F Bacic; R M McCarron; S Uematsu; M Spatz
Journal:  Metab Brain Dis       Date:  1992-09       Impact factor: 3.584

2.  Adrenergic receptors in Alzheimer's disease brain: selective increases in the cerebella of aggressive patients.

Authors:  A Russo-Neustadt; C W Cotman
Journal:  J Neurosci       Date:  1997-07-15       Impact factor: 6.167

Review 3.  Neuronal control of brain microvessel function.

Authors:  H Kobayashi; M S Magnoni; S Govoni; F Izumi; A Wada; M Trabucchi
Journal:  Experientia       Date:  1985-04-15

Review 4.  Autonomic function and brain volume.

Authors:  Juan M Racosta; Kurt Kimpinski
Journal:  Clin Auton Res       Date:  2016-08-27       Impact factor: 4.435

5.  Adrenergic, serotoninergic, histaminergic, and imipramine binding sites in post-mortal human cerebral microvessel preparations.

Authors:  C O'Neill; C J Fowler; J O Marcusson; B Winblad
Journal:  J Neural Transm       Date:  1988       Impact factor: 3.575

6.  Beta-adrenergic receptor activity of cerebral microvessels is reduced in aged rats.

Authors:  A D Mooradian; P J Scarpace
Journal:  Neurochem Res       Date:  1991-04       Impact factor: 3.996

7.  Effect of acute and prolonged treatment with propranolol on cerebral blood flow and cerebral oxygen metabolism in healthy volunteers.

Authors:  P L Madsen; S Vorstrup; J F Schmidt; O B Paulson
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953
  7 in total

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