Literature DB >> 6292294

Structure of the murine plasma cell alloantigen PC-1: comparison with the receptor for transferrin.

J W Goding, F W Shen.   

Abstract

The plasma cell alloantigen PC-1 was isolated from C1.18 myeloma cells by immunoprecipitation and was analyzed by polyacrylamide gel electrophoresis. It was found to consist of two similar or identical disulfide-bonded polypeptide chains, each of Mr 115,000. The mobility of PC-1 in nonequilibrium pH gradient electrophoresis was similar to that of bovine serum albumin (pI 4.9). The PC-1 antigen is therefore similar to the transferrin receptor in Mr, charge, subunit composition, disulfide bonding, and developmental regulation. Similarities can also be detected by peptide mapping with subtilisin, but not with staphylococcal V8 protease. It is suggested that the PC-1 protein and the transferrin receptor may have had a common evolutionary origin, and may have similar functions.

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Year:  1982        PMID： 6292294

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  8 in total

1.  Plasma cell membrane glycoprotein gene Pca-1 (alkaline phosphodiesterase I) is linked to the proto-oncogene Myb on mouse chromosome 10.

Authors:  M F Buckley; J W Goding
Journal:  Immunogenetics       Date:  1992       Impact factor: 2.846

2.  Murine plasma cell antigen PC-1 has a region homologous to the active site of bovine intestinal 5'-nucleotide phosphodiesterase I (EC 3.1.4.1).

Authors:  M A Skinner
Journal:  Nucleic Acids Res       Date:  1991-11-11       Impact factor: 16.971

3.  Murine plasma cell membrane antigen PC-1: molecular cloning of cDNA and analysis of expression.

Authors:  I R van Driel; A F Wilks; G A Pietersz; J W Goding
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

Review 4.  Cellular function and molecular structure of ecto-nucleotidases.

Authors:  Herbert Zimmermann; Matthias Zebisch; Norbert Sträter
Journal:  Purinergic Signal       Date:  2012-05-04       Impact factor: 3.765

5.  Characterization of a new plasma membrane-associated ecto-5'-phosphodiesterase/nucleotide-pyrophosphatase from rat hepatocarcinoma AS-30D cells.

Authors:  R M García-Nieto; E S José; J Martín-Nieto; A Villalobo
Journal:  J Physiol Biochem       Date:  2001-03       Impact factor: 4.158

6.  Phosphorylation and nucleotide-dependent dephosphorylation of hepatic polypeptides related to the plasma cell differentiation antigen PC-1.

Authors:  M Uriarte; W Stalmans; S Hickman; M Bollen
Journal:  Biochem J       Date:  1993-07-01       Impact factor: 3.857

7.  Divalent cations stabilize the conformation of plasma cell membrane glycoprotein PC-1 (alkaline phosphodiesterase I).

Authors:  S I Belli; A Sali; J W Goding
Journal:  Biochem J       Date:  1994-11-15       Impact factor: 3.857

8.  Effects of two major activating lesions on the structure and conformation of human ras oncogene products.

Authors:  S K Srivastava; Y Yuasa; S H Reynolds; S A Aaronson
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205
  8 in total

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